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Traditional Chinese medicine composition for resisting inflammation and repairing skin barrier, extracts and preparation

A technology of repairing skin and traditional Chinese medicine preparations, which is applied in the field of extracts and preparations, anti-inflammatory and skin barrier repairing traditional Chinese medicine compositions, which can solve the problems of intractable cases such as helplessness, decline in curative effect, and inability to meet clinical needs, and achieve improvement of skin itching , the effect of less adverse reactions

Inactive Publication Date: 2018-09-11
CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

External use of glucocorticoids in the treatment of eczema may achieve better results in the early stage, but may lead to glucocorticoid dependence and drug withdrawal relapse
In addition, there are often problems in long-term clinical practice: the initial application of glucocorticoid preparations usually shows good results, but after a few days of continued use, the curative effect decreases significantly, and rapid desensitization and tolerance of externally applied hormones appear, almost helpless for intractable cases
Clinically, there are few Chinese patent medicines for treating chronic eczema. They mainly include Binghuangfule ointment, Chushi Zhiitch ointment, and Centai ointment. The main treatment is anti-inflammatory, which cannot meet the clinical needs.

Method used

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  • Traditional Chinese medicine composition for resisting inflammation and repairing skin barrier, extracts and preparation
  • Traditional Chinese medicine composition for resisting inflammation and repairing skin barrier, extracts and preparation

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Experimental program
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Effect test

Embodiment 1

[0026] Eczema is a common chronic, recurrent inflammatory and skin barrier destruction skin disease. It is mainly manifested as a pleomorphic skin rash and a tendency to exudate, and severe itching leads to repeated scratching. After conducting research on the constitution theory of traditional Chinese medicine, it is found that in the physique classification of patients with eczema, yin deficiency constitution accounts for the highest proportion, which is statistically significant compared with healthy people. Mainly due to the long-term pathogenesis of eczema patients, which will enter the network for a long time. On the one hand, it will form damp-heat stasis, which is difficult to remove. Itching. Over time, the patient's yin-deficiency physique was gradually exposed and the performance was adequate.

[0027] The method of "sour and sweetness to transform yin" is to use two kinds of medicines with different nature and taste functions, sour and sweet. Sour medicines mostly en...

Embodiment 2

[0032] This embodiment provides an anti-inflammatory and skin barrier-repairing traditional Chinese medicine lotion liquid, which is composed of the following raw materials in parts by weight: 10 parts of licorice, 5 parts of purslane, and 10 parts of scutellaria.

[0033] Weigh Chinese herbal medicine pieces according to the above-mentioned ratio, add 40-80 times the amount of water, decoct for 30-60 minutes, and add appropriate amount of preservative to the decoction.

Embodiment 3

[0035] This embodiment provides an anti-inflammatory and skin barrier-repairing traditional Chinese medicine lotion solution, which is composed of the following raw materials in parts by weight: 5 parts of licorice, 15 parts of purslane, and 5 parts of scutellaria.

[0036] Weigh Chinese herbal medicine pieces according to the above ratio, add 30-50 times the amount of 30%-75% ethanol and decoct for 1 to 2 times, each time of 25-40 minutes, and combine the decoction to obtain.

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Abstract

The invention discloses a traditional Chinese medicine composition for resisting inflammation and repairing skin barrier. The traditional Chinese medicine composition is prepared from, by weight, 5-15parts of licorice root, 5-15 parts of herba portulacae and 5-15 parts of radix scutellariae. According to the traditional Chinese medicine composition, the new external treatment concept of nourishing the yin with sour and sweet is put forward for the first time according to the yin deficiency characteristic of eczema; itching stopping is achieved through sour medicines, urgency relieving and skin moistening are realized in combination with sweet medicines, and the itching stopping, inflammation eliminating and skin barrier repairing functions are achieved. The invention further provides extracts and a preparation prepared from the traditional Chinese medicine composition. Through animal experiment and clinical test results, it shows that the composition has inflammation resisting and skin barrier repairing effects, can remarkably improve skin pruritus, erythema, papule, skin lesion and the like, causes little adverse reaction and is particularly suitable for treating eczema and atopic dermatitis.

Description

Technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, extract and preparation for anti-inflammatory and repairing skin barrier. Background technique [0002] Skin inflammation and destruction of the skin barrier are characteristic of most skin diseases. Anti-inflammatory and repairing the skin barrier have become an important strategy for the treatment of dermatitis, eczema (atopic dermatitis) and other refractory skin diseases. [0003] Symptomatic skin diseases such as dermatitis and eczema occur repeatedly because of itching, and the skin barrier is damaged, which seriously affects the patient's physical and mental health, and also affects the patient's work and life. Eczema is an inflammatory skin disease with obvious exudative tendency caused by a variety of factors. Its main characteristics are polymorphic skin lesions, itching, and easy recurrence; atopic dermatitis is related ...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61P17/00A61P29/00
CPCA61K36/185A61K36/484A61K36/539A61P17/00A61P29/00A61K2300/00
Inventor 刁庆春刘毅陶春蓉李敏高燕妮杨富金
Owner CHONGQING TRADITIONAL CHINESE MEDICINE HOSPITAL
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