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Microwave hyperthermia monitoring method based on ultrasonic echo decorrelation imaging technology

A technology of microwave hyperthermia and ultrasonic echo, applied in the field of signal processing, can solve the problems of high cost, unsuitable for long-term monitoring, real-time performance and low imaging resolution, and achieve the effect of reducing tissue cavitation

Active Publication Date: 2018-09-21
BEIJING UNIV OF TECH
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Problems solved by technology

MRI has high precision in measuring tissue temperature during hyperthermia, but its real-time and imaging resolution are not high, and the cost is expensive; CT has certain radiation to the human body and is not suitable for long-term monitoring; USI is famous for its nondestructive , good real-time performance and low cost have become the research objects of many scholars
Traditional ultrasound imaging is easily affected by air bubbles generated during hyperthermia, causing artifacts below the air bubbles and cannot accurately describe the coagulation area

Method used

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  • Microwave hyperthermia monitoring method based on ultrasonic echo decorrelation imaging technology
  • Microwave hyperthermia monitoring method based on ultrasonic echo decorrelation imaging technology
  • Microwave hyperthermia monitoring method based on ultrasonic echo decorrelation imaging technology

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Embodiment Construction

[0027] Such as figure 1 Shown is a flow chart of the method of the present invention, which mainly includes maximum accumulative decorrelation imaging based on ultrasonic echo signals and coagulation zone delineation based on accumulative decorrelation images.

[0028] Such as figure 2 As shown, the ultrasonic echo transient decorrelation imaging specifically includes:

[0029] Step 1. Continuously collect ultrasonic echo signals data_1, data_2...data_N at different moments of microwave hyperthermia;

[0030] Step 2. Perform Hilbert transform on two adjacent frames of ultrasound data data_K and data_K+1 to obtain complex analysis signals I_K and I_K+1;

[0031] Step 3. Perform Gaussian convolution filtering on I_K.*conj(I_K+1), abs(I_K).^2 and abs(I_K+1).^2 respectively to obtain R01, R00 and R11;

[0032] Step 4. According to the formula 2*(R00.*R11-abs(R01).^2). / (R00.*R11+mean(mean(R00.*R11))) calculate the instantaneous mean value of two adjacent frames of ultrasound da...

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Abstract

The invention provides a microwave hyperthermia coagulation area detecting method based on an ultrasonic decorrelation imaging technology. Ultrasonic echo signals at different moments of microwave hyperthermia are continuously collected. Instantaneous decorrelation imaging (decorrelation imaging of ultrasonic signals of every two adjacent frames) and maximum cumulative decorrelation imaging (the maximum value of each pixel in all instantaneous decorrelation images) are carried out respectively. A threshold is set. A coagulation area is depicted in a cumulative decorrelation image. A polynomialfitting technology is combined to realize quantitative detection of the microwave hyperthermia coagulation area. According to the invention, all ultrasonic signals are collected during a hyperthermiaprocess; the influence of signal mutation caused by cavitation can be reduced; and the detection accuracy of the coagulation area is improved.

Description

technical field [0001] The invention belongs to the field of signal processing, in particular to a microwave hyperthermia monitoring method based on ultrasonic echo decorrelation imaging technology. Background technique [0002] Liver cancer is one of the common malignant tumors, and surgical resection is currently considered the first choice for the treatment of liver cancer. However, due to factors such as tumor location, size, and surrounding blood vessels, only a small number of patients are suitable for surgery. In recent years, thermal ablation has emerged as an effective novel therapy for liver tumors. Microwave hyperthermia has attracted widespread attention due to its characteristics of not being affected by current conduction, less affected by carbonization and blood perfusion, rapid temperature rise, and large ablation range. In order to ensure the maximum range of killing tumor cells and protecting normal tissue cells during hyperthermia, the quantitative real-...

Claims

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Application Information

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IPC IPC(8): A61N5/02A61B8/08
CPCA61B8/0833A61N5/025
Inventor 吴水才王月周著黄欧阳亚丽高宏建
Owner BEIJING UNIV OF TECH
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