37 results about "Microwave hyperthermia" patented technology

A microwave hyperthermia apparatus that can be inserted into the body which includes a hollow central tube for the insertion of radioactive therapy sources. The use of a coaxial transmission line impedance transformation along the insertable portion of the coaxial cable enables a reduction in the characteristic impedance by increasing the outer diameter of the inner coaxial conductor so that the center conductor can be a metal tube. If the ratio of the outer coaxial conductor diameter vs. the inner coaxial conductor is decreased, the characteristic impedance of the transmission line is lowered. This enables the inner conductor diameter to increase sufficiently to make the central hollow opening large enough to receive standard radioactive sources therein. This provides for a good impedance match that improves microwave energy efficiency while at the same time permitting a large hollow center opening. The combination of the microwave antenna device and brachytherapy sources provides for enhanced effectiveness when the two treatments are delivered simultaneously or in close time proximity to each other.

The invention discloses application of chemoembolization porous microspheres with a microwave sensitization function in preparing a medicine or preparation for treating tumor. The adsorbate of the microspheres is inorganic salt and a chemotherapy medicine, the skeleton of the microspheres is poly(lactide-co-glycolide), the diameter of the microspheres is 20-700mu m, and the specific surface is greater than 10m<2>/g. The invention also provides a preparation method of the chemoembolization porous microspheres. The chemoembolization porous microspheres disclosed by the invention have good microwave sensitization heating and tumor blood vessel embolization function, exhibit regular spherical shapes, and have high porosity, narrow particle size distribution and controllable particle size; in addition, the chemoembolization microspheres with microwave sensitization prepared from the poly(lactide-co-glycolide) are applied to treatment of cancer for the first time, acquire an excellent tumor inhibiting effect and have good clinical application value.

The invention discloses a near-field active mirror image focusing antenna, which comprises a receiving antenna array, a transmitting antenna array, a phase conjugate circuit module, an illuminating antenna, a base and an illuminating antenna mobile station. The near-field active mirror image focusing antenna can be used for microwave hyperthermia, microwave detection and microwave energy transmission. The near-field active mirror image focusing antenna has the advantages that a focal position is controllable, multiple focuses can be formed, low side-lobe amplitude distribution is formed on a transmitting aperture surface in a self-adaptive manner, and the focusing effect is excellent.

The invention discloses a sodium alginate microcapsule for tumor microwave hyperthermia technology. The diameter of the microcapsule is 1-10 microns, and the shell thickness of the microcapsule is 100-1000 nm. According to the invention, the sodium alginate microcapsule is firstly applied to the technical field of tumor microwave hyperthermia, and an excellent curative effect is obtained, so that the diagnosis and treatment efficiency is greatly improved, and an excellent clinical application value is provided.

The invention discloses an anticancer biological film nano target cooperated plastid and a preparing method thereof. The cooperated plastid is prepared from, by weight, 160-250 parts of lecithin, 40-60 parts of soluble protein, 10-50 parts of target polypeptide and 5-20 parts of soluble meta salt. The prepared anticancer biological film nano target cooperated plastid is easily fused with a cell membrane, the biocompatibility, the targeting performance, the degradability, the bioavailability and the stability of drugs can be improved, the degradability is high, the anticancer biological film nano target cooperated plastid is safe and poisonous to the human body, and normal tissue cells are not damaged; the anticancer biological film nano target cooperated plastid can serve as a tumor diagnosis reagent, a carrier for of drugs for resisting cancer, a transgene carrier, a photo-thermal photodynamic therapeutic agent, an ultrasonic photodynamic therapeutic carrier, a radio frequency and microwave hyperthermia carrier, a medical image reinforcing agent and the like.

Provided is a device for microwave hyperthermia that may attach a flexible patch on the skin of a user based on a cross-section of a body tissue of the user, for example, a joint and muscle of a leg and an arm and may emit microwaves towards a plurality of points of the body tissue through the patch. The microwaves emitted toward the body tissue may have the same phase and maximum power. Accordingly, a maximum heat generation point may be generated in an area adjacent to the plurality of points. The device for microwave hyperthermia may move the maximum heat generation point by sequentially changing a phase and a direction of each of the microwaves. The device for microwave hyperthermia may uniformly distribute and maintain heat for treating pain and/or infection over the entire cross-section or a partial area. The device for microwave hyperthermia may be portable.

The invention relates to an anti-microwave-interference temperature measurement and ablation integrated semi-rigid water-cooling microwave ablation antenna. The antenna comprises a radiation head, a medium pipe, a semi-rigid coaxial cable and a thermocouple. The antenna is characterized in that a metal shielding case is arranged outside the radiation head; the temperature measurement end of the thermocouple is fixed on the inner surface of the metal shielding case. The anti-microwave-interference temperature measurement and ablation integrated semi-rigid water-cooling microwave ablation antenna can be used for reliably shielding action and serious interference of microwave energy and microwave electromagnetic field intensity on the temperature measurement end by using the perfect structure, so that the critical technology of measuring the actual temperature of an ablated tumor in real time when the semi-rigid microwave ablation antenna is used for performing microwave ablation treatment in cavity, intestinal tract or vessels, even in the heart can be achieved. Therefore, reliable guarantee is provided to excellent curative effect and application expansion of microwave clinical treatment, and a beneficial condition is created for semi-rigid microwave ablation or microwave hyperthermia intelligence.

A microwave hyperthermia instrument based on a DSP (digital signal processor) platform comprises a microwave source, a temperature sensor, a single chip microcomputer, a DSP chip, a central processing unit, a storage and a displayer. The single chip microcomputer is connected with the microwave source, the temperature sensor, the DSP chip and the central processing unit, and the storage and the displayer are connected with the central processing unit. The microwave hyperthermia instrument based on the DSP platform has the advantages that a control system of the microwave hyperthermia instrument is improved by the embedded technology, thereby being improved in terms of miniaturization, intellectualization, accuracy improvement and cost reduction greatly; the microwave hyperthermia instrument can be compatible to popular microwave emitters in the market due to multiple interfaces thereon, and has high expandability.

The invention discloses a medical lung microwave physiotherapy oscillation sputum excretion device. The device comprises an oscillation sputum excretion machine, a sputum excretion waistcoat, air guide hoses, a microwave physiotherapy instrument, a microwave physiotherapy head, a physiotherapy line and a microwave distance adjuster. The microwave distance adjuster comprises a fixed base and a sliding base, the fixed base is in sliding connection with the sliding base, and the fixed base is fixed to the back of the sputum excretion waistcoat. Between two shoulder blades of a patient, the microwave physiotherapy head is arranged in the sliding seat, the sliding seat drives the microwave physiotherapy head to slide on the fixed seat, the distance between the microwave physiotherapy head and the back of the patient is adjusted, the oscillation sputum excretion machine is connected with the sputum excretion waistcoat through the air guide hoses, and the microwave physiotherapy instrument is connected with the microwave physiotherapy head through the physiotherapy wire. A microwave heating physiotherapy system is arranged on the basis of an existing oscillating sputum excretion machine, a patient who has sputum in the lung and is not prone to coughing can be effectively helped to coughing out sputum, the burden of medical staff is relieved, torture of the patient due to pain are relieved, and rehabilitation of the patient is facilitated.

The invention discloses a copper, zinc, tin and sulfur quaternary nanocomposite with functions of microwave sensitization and nuclear magnetic imaging and a preparation and application method thereof. The copper, zinc, tin and sulfur quaternary nanocomposite with functions of microwave sensitization and nuclear magnetic imaging comprises nano copper, zinc, tin and sulfur compound and biocompatible molecules on the surface of the compound. By the copper, zinc, tin and sulfur quaternary nanocomposite with the functions of microwave sensitization and nuclear magnetic imaging, microwave hyperthermia and microwave induced photodynamic therapy can be combined together. The copper, zinc, tin and sulfur quaternary nanocomposite with functions of microwave sensitization and nuclear magnetic imaging has an excellent tumor treatment effect.

The invention discloses in-vitro thermal therapy equipment and an in-vitro microwave thermal therapy antenna thereof. The in-vitro thermal therapy equipment comprises a coaxial input line, at least two groups of microstrip patches and a metal conductor sleeve, wherein the input end of the coaxial input line is electrically connected with the in-vitro thermal therapy equipment through a connector, each group of microstrip patches is connected with the coaxial input line, each group of microstrip patches are arranged in the axial direction of the coaxial input line, the microstrip patch located at the tail end is attached to the skin of a patient, and the microstrip patch located at the tail end is attached to the skin of the patient. The metal conductor sleeve sleeves the outer ring of the coaxial input line and is connected with the microstrip patch at the beginning end to form a grounding end. The metal conductor sleeve and the microstrip patch form a grounding end together, so that the antenna can still have enough grounding area when the size is small, the antenna has no special requirement on external environment, can be directly used in air, can have small size, and provides technical conditions for designing miniaturized microwave hyperthermia equipment.

The invention provides a microwave hyperthermia coagulation area detecting method based on an ultrasonic decorrelation imaging technology. Ultrasonic echo signals at different moments of microwave hyperthermia are continuously collected. Instantaneous decorrelation imaging (decorrelation imaging of ultrasonic signals of every two adjacent frames) and maximum cumulative decorrelation imaging (the maximum value of each pixel in all instantaneous decorrelation images) are carried out respectively. A threshold is set. A coagulation area is depicted in a cumulative decorrelation image. A polynomialfitting technology is combined to realize quantitative detection of the microwave hyperthermia coagulation area. According to the invention, all ultrasonic signals are collected during a hyperthermiaprocess; the influence of signal mutation caused by cavitation can be reduced; and the detection accuracy of the coagulation area is improved.

The invention relates to a thermotherapy microwave diagnosis and treatment device for orthopedic diseases, which belongs to the technical field of medical instruments. The microwave diagnosis and treatment device for orthopedic diseases of the present invention comprises a main body, a power sensor board is arranged on the rear side of the main body, a microwave diagnosis box is arranged on the upper side of the main body, a microwave display is arranged on the front side of the microwave diagnosis box, and a microwave display is arranged on the rear side of the microwave diagnosis box. Absorbing carrier plate, radiation absorbing block is arranged on the rear side of the absorbing carrier plate, emergency power supply production device and therapeutic microwave production column are arranged inside the microwave diagnostic box, therapeutic instrument storage box and orthopedic disease thermotherapy box are arranged inside the main body, and orthopedic disease hyperthermia A heat producing body is arranged inside the box, a medical steam storage box is provided on the upper side of the heat production body, and a pressure sensing guide rod is provided on the left side of the medical steam storage box. The invention has complete functions and is convenient to use. When the medical staff conducts pathological diagnosis and analysis of patients, it saves time and labor, is scientific and convenient, is safe and efficient, intelligent and accurate, and reduces the work difficulty of the medical staff.

Microwave hyperthermia treatment device includes a microwave generation unit, a power supply unit, and a control unit including an exposure-time actuation timer, an intermittent actuation timer, a second-device connecting terminal, and a remote switch. Two microwave hyperthermia treatment devices are connected with each other via the second terminal connecting terminals for simultaneous use flanking the torso along either side of an affected area, whereby superposed strong microwaves are irradiated. The temperature of tumor(s) in the affected area can thereby be brought to about 43° C. in about 1 minute, rendering lengthy treatment periods unnecessary and thus alleviating temperature stress on the patient. Two remote-control switches to the control unit can be provided, one of which may be given to a patient for use as an emergency stop switch, eliminating the necessity of having to insert a temperature sensor in the body, which also alleviates the burden on the patient.