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Applications of Valeriana jatamansi Jones extract in preparation of drugs for restoring damaged small intestine villi or relieving intestinal mucosal barrier damage

A technology of barrier damage and spider scent, which is applied in the field of medicine and biology, can solve the problems of small intestine villi that have not yet been seen, and achieve the effect of alleviating intestinal mucosal barrier damage

Inactive Publication Date: 2018-11-06
云南龙发制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are many studies on the cultivation of spider incense as raw material, but there are no research reports on the effective components of spider incense for restoring damaged small intestinal villi or alleviating intestinal mucosal barrier damage

Method used

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  • Applications of Valeriana jatamansi Jones extract in preparation of drugs for restoring damaged small intestine villi or relieving intestinal mucosal barrier damage
  • Applications of Valeriana jatamansi Jones extract in preparation of drugs for restoring damaged small intestine villi or relieving intestinal mucosal barrier damage
  • Applications of Valeriana jatamansi Jones extract in preparation of drugs for restoring damaged small intestine villi or relieving intestinal mucosal barrier damage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] A preparation method of spider incense extract, comprising the following steps:

[0039] Take the spider incense, extract it with ethanol with a concentration of 95% by volume at room temperature, concentrate the extract to obtain an extract; dissolve the extract with ethyl acetate, filter, and dry the obtained filtrate to obtain (VJ03).

Embodiment 2

[0041] A preparation method of spider incense extract, comprising the following steps:

[0042] Take the spider incense, extract it with ethanol with a concentration of 95% by volume at room temperature, concentrate the extract to obtain an extract; dissolve the extract with ethyl acetate, filter, dry the obtained filtrate, add petroleum ether to dissolve, and The petroleum ether solution was dried to obtain (VJ01).

Embodiment 3

[0044] A preparation method of spider incense extract, comprising the following steps:

[0045] Take the spider incense, extract it with ethanol with a concentration of 95% by volume at room temperature, concentrate the extract to obtain an extract; dissolve the extract with ethyl acetate, filter, dry the obtained filtrate, add petroleum ether to dissolve, and then The insoluble part of petroleum ether was dried to obtain (VJ02).

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Abstract

The invention discloses applications of a Valeriana jatamansi Jones extract in preparation of drugs for restoring damaged small intestine villi or relieving intestinal mucosal barrier damage. The preparation method of the Valeriana jatamansi Jones extract comprises: taking Valeriana jatamansi Jones, carrying out room temperature leaching with ethanol having a volume percentage concentration of 95%, and concentrating the leaching solution to obtain an extract; dissolving the extract by using ethyl acetate; and filtering, and drying the obtained filtrate to obtain the product. According to the present invention, the obtained Valeriana jatamansi Jones extract can restore damaged small intestine villi or relieve intestinal mucosal barrier damage.

Description

technical field [0001] The invention belongs to the field of medicine and biology, and specifically relates to the application of a spider incense extract in preparing a medicine for restoring damaged small intestinal villi or alleviating intestinal mucosal barrier damage. Background technique [0002] The traditional Chinese medicine spider incense is the dried rhizome and root of Valeriana jatamansi Jones, a plant of the genus Patinaceae, which has rich medicinal value. It was first recorded in "Compendium of Materia Medica": "Eliminate the plague and neutralize the evil". "Yunnan Chinese Herbal Medicine" records: "Cure indigestion, cough in children, malnutrition, flu, malaria", it is one of the commonly used medicines in Yunnan. Spider incense is slightly bitter, pungent and mild in nature. Traditional Chinese medicine believes that it has the effects of regulating qi and relieving pain, eliminating food and diarrhea, dispelling wind and dampness, and calming the nerves...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/84A61P1/00
CPCA61K36/84A61K2236/333A61P1/00
Inventor 焦家良焦少良徐志斌陈勇许杰吉翠莲
Owner 云南龙发制药股份有限公司
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