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Soybean fermentation metabolin and application thereof

A technology for soybean fermentation and metabolites is applied to soybean fermentation metabolites and their application fields to achieve the effects of preventing skin-related diseases, avoiding loss and maintaining balance

Active Publication Date: 2018-11-23
仙婷(广州)科技研发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there is no report linking soybean ferment and skin barrier

Method used

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  • Soybean fermentation metabolin and application thereof
  • Soybean fermentation metabolin and application thereof
  • Soybean fermentation metabolin and application thereof

Examples

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Effect test

Embodiment 1

[0033] An embodiment of soybean fermentation metabolites of the present invention includes amino acids and derivatives thereof, amines, phosphate sugars, nucleosides, nucleoside derivatives, vitamin metabolites, organic acids and fatty acids; soybean fermentation metabolites also contain ten Hexaamide ethanol (1.526), ​​5-aminolevulinic acid (0.127), resveratrol (0.002), kaempferol (0.157) and rubber extract (0.007).

[0034]Among them, the amino acids are alanine (15.212), threonine (2.03), L-asparagine (4.752), L-citrulline (0.576), oxidized glutathione (0.017), tryptophan and arginine amino acid (0.19), amino acid derivatives are D-alanyl-D-alanine (1.25), hydroxymethyllysine (0.024), theanine (4.752), thioproline (0.492) , carbamoyl-DL-aspartic acid (0.096), N-acetylglutamic acid (0.820), 2-methylserine (0.528) and O-acetyl-L-serine (0.549); amine is acetylglucose Amine (0.826), trimethylamine (0.057), N-acetamide (0.027), diethyltoluamide (0.273), acylcholine (0.124), pu...

Embodiment 2

[0040] An embodiment of soybean fermentation metabolites of the present invention includes amino acids and derivatives thereof, amines, phosphate sugars, nucleosides, nucleoside derivatives, vitamin metabolites, organic acids and fatty acids; soybean fermentation metabolites also contain ten Hexaamide ethanol (2.002), 5-aminolevulinic acid (0.273), resveratrol (0.007), kaempferol (0.095) and rubber extract (0.018).

[0041] Among them, the amino acids are alanine (13.608), threonine (2.26), L-asparagine (3.801), L-citrulline (0.881), oxidized glutathione (0.033), tryptophan and arginine Amino acid (0.33), amino acid derivatives are D-alanyl-D-alanine (1.047), hydroxymethyllysine (0.074), theanine (4.246), thioproline (0.214) , carbamoyl-DL-aspartic acid (0.243), N-acetylglutamic acid (0.668), 2-methylserine (0.153) and O-acetyl-L-serine (0.173); amine is acetylglucose Amine (0.201), trimethylamine (0.233), N-acetamide (0.144), diethyltoluamide (0.064), acylcholine (0.366), pu...

Embodiment 3

[0047] An embodiment of soybean fermentation metabolites of the present invention includes amino acids and derivatives thereof, amines, phosphate sugars, nucleosides, nucleoside derivatives, vitamin metabolites, organic acids and fatty acids; soybean fermentation metabolites also contain ten Hexaamide ethanol (3.154), 5-aminolevulinic acid (0.416), resveratrol (0.013), kaempferol (0.055) and rubber essence (0.026).

[0048] Among them, the amino acids are alanine (11.008), threonine (2.65), L-asparagine (2.553), L-citrulline (1014), oxidized glutathione (0.057), tryptophan and arginine Amino acid (0.65), amino acid derivatives are D-alanyl-D-alanine (2.211), hydroxymethyllysine (0.519), theanine (2.369), thioproline (0.568) , carbamoyl-DL-aspartic acid (0.119), N-acetylglutamic acid (0.961), 2-methylserine (0.438) and O-acetyl-L-serine (0.654); amine is acetylglucose Amine (0.875), trimethylamine (0.171), N-acetamide (0.745), diethyltoluamide (0.256), acylcholine (0.885), put...

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Abstract

The invention discloses a soybean fermentation metabolin. Components of the metabolin comprise amino acid and a derivative thereof, amine, sugar phosphate, nucleoside, a nucleoside derivative, organicacid and fatty acid. In addition, the invention further discloses a preparation method and application of the soybean fermentation metabolin. The soybean fermentation metabolin has the remarkable effects of improving diversity and quality of skin bacterial flora, skin water content and skin acid mantle, and is capable of avoiding loss of skin beneficial substances, maintaining balance of the skinbacterial flora, reinforcing nonspecific immune response, preventing skin infection and inflammation, and preventing skin related diseases, such as pruritus, acne, scurf, rubeosis and drying.

Description

technical field [0001] The invention relates to the technical field of soybean fermentation, in particular to a soybean fermentation metabolite and its application. Background technique [0002] The skin is composed of a variety of ecological niches, including regions of widely varying pH, temperature, humidity, and sebum content. Measurements of pH and moisture content in the stratum corneum of the skin surface are useful for objective evaluation of some non-invasive techniques for the treatment of atopic dermatitis as well as physical parameters of the skin barrier. In addition, the skin structure is also related to its unique microbiota, such as hair follicles, sebaceous glands, eccrine glands, and apocrine glands, which are all secondary habitats for microorganisms. The skin barrier prevents the evaporation of water and the ingress of infectious or toxic substances, which are essential for survival. Skin is also a complex habitat for diverse populations of microbiota. ...

Claims

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Application Information

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IPC IPC(8): C12P1/04A61K8/9789A61Q19/00C12R1/225C12R1/01C12R1/46
CPCA61K2800/85A61Q19/00A61K8/9789C12P1/04C12N1/205C12R2001/01C12R2001/225C12R2001/46
Inventor 让-伊夫 布鲁克瑟周雯付毅敏
Owner 仙婷(广州)科技研发有限公司
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