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Herba epimedii traditional Chinese medicine composition for tonifying kidney, benefiting essence and blood and improving immunity

A pressure and extract technology, applied in the field of Chinese medicinal composition of Epimedium and Rhodiola, can solve the problems of poor synergy, poor effect, low content of pharmacologically active ingredients, etc., and achieve the effect of good fracture resistance and toughness

Active Publication Date: 2018-12-11
安徽九鑫药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] In summary, there are still multiple defects in the prior art, especially the extracting method of Snow Lotus in the prior art is still using the traditional extraction method, although there are reports of using supercritical methods to extract the pharmacologically active substances of Snow Lotus, but still It is the conventional supercritical extraction equipment and process used, the content of pharmacologically active ingredients in the extract is low, and the content of undesired impurities is relatively high
In addition, there is no report on the compound preparation of snow lotus extract, epimedium extract and Rhodiola rosea extract, or usually the three extracts containing complex components, that is, crude extracts, are not only effective. Poor, and less synergistic

Method used

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  • Herba epimedii traditional Chinese medicine composition for tonifying kidney, benefiting essence and blood and improving immunity
  • Herba epimedii traditional Chinese medicine composition for tonifying kidney, benefiting essence and blood and improving immunity
  • Herba epimedii traditional Chinese medicine composition for tonifying kidney, benefiting essence and blood and improving immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] The snow lotus used for extraction is Tianshan snow lotus (purchased from Urumqi Beiyuan Chun Agricultural and Sideline Products Management Co., Ltd.). The extraction device used includes: an inlet section, an extraction section, and an outlet section, the inlet section may include: a carbon dioxide supply storage tank (1), valves (2, 4, 7) connected to a pressure gauge (5), compression machine (3), carbon dioxide storage container (6), high-pressure pump (8), coil (9) and CO towards the extraction tank (11) 2 Inlet valve (10); the extraction part may include: an extraction tank (11), a pressure gauge (12) connected to the extraction tank, a light bulb (13), a fan (14) for temperature uniformity and precision The heating system that thermometer is formed, and described precision thermometer is connected with temperature controller (15) and is used for measuring temperature, and described outlet part can comprise: the outlet valve (16) of extraction pond, extract collect...

Embodiment 2

[0066] The inhibitory effect of the Saussureae extract of Example 1 on the secondary damage of adjuvant arthritis was tested.

[0067] Take 60 Wistar rats, half male and half female, body weight 150-200g, half male and half male, and randomly divided into 3 groups, i.e. normal control group, conventional extract group (0.05g kg -1 , control group, wherein the Snow Lotus extract is obtained according to the method recorded in CN101041653B), Example 1 extract group (0.05g·kg -1 ); first use the toe volume measuring instrument to measure the volume of the left hind paw of each group of rats as the base value. Except for the normal control group, all other groups were subcutaneously injected with 0.1 mL of Freund's complete adjuvant on the right hind paw, and each administration group began to administer by intragastric administration on the 12th day after inflammation, and the normal control group and the model group were intragastrically administered with the same amount of Dis...

Embodiment 3

[0074] The preparation of the capsule that comprises Snow Lotus extract, Epimedium extract and Rhodiola rosea extract, wherein get the Saussurea oleifera extract described in embodiment 1, the aforementioned Epimedium extract and Rhodiola rosea extract, Snow lotus The weight ratio of extract, epimedium extract and rhodiola rosea extract is 8:1:1, and each capsule contains 0.1g of contents. The capsule is carried out according to the method of embodiment 2 to the inhibition test of the secondary damage of adjuvant arthritis, under the same dose and experimental conditions, the toe swelling degree (ml) on the 3rd day after causing inflammation is 0.86 ± 0.11.

[0075] It can also be seen from Examples 2 and 3 that the addition of Epimedium extract and Rhodiola rosea extract has enhanced the anti-inflammatory effect of Saussurea sauraceae extract, and has a better effect of improving immunity and anti-fatigue. It is speculated that in addition to the anti-inflammatory effects of...

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Abstract

The invention discloses a herba epimedii and rhodiola rosea traditional Chinese medicine composition for tonifying kidney, benefiting essence and blood and improving immunity, as well as a saussurea involucrate extraction apparatus. The extraction apparatus is high in efficiency, and capable of maximally reducing side products in the extraction process, so that the obtained extract is high in pharmacological activity. The composition has the efficacies for improving the immunity, resisting the inflammation, resisting the fatigue, resisting the radiation, tonifying the kidney, and benefiting the essence and blood.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine composition of Epimedium Rhodiola for invigorating the kidney, benefiting essence and blood, and enhancing immunity, a supercritical extracting device of Snow Lotus, a Chinese medicine composition containing Saussurea Saussurea extract and a preparation method thereof, in particular to a method for improving Immunity, anti-inflammation, anti-fatigue, anti-radiation, kidney-tonifying, and blood-tonifying traditional Chinese medicine composition, the traditional Chinese medicine composition is especially a composition comprising Saussurea sauraceae extract, Epimedium extract and Rhodiola rosea extract, that is Saussurea sauraceae Epimedium rhodiola rosea traditional Chinese medicine composition. Background technique [0002] Snow lotus is a rare and precious Chinese medicinal material in my country. It has a long history of use and a rich folk medicine foundation. The flavonoids and their gl...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/285A61K36/41A61P37/04A61P39/00A61P1/14A61P13/12A61P7/06A61P29/00B01D11/02A23L2/38
CPCA61P1/14A61P7/06A61P13/12A61P29/00A61P37/04A61P39/00B01D11/0203B01D11/0207B01D11/0265A23L2/38A23L33/105A61K36/285A61K36/296A61K36/41C21D1/26C21D6/004C21D6/04C22C38/02C22C38/04C22C38/06C22C38/44C22C38/50A23V2002/00A61K2236/37A61K2300/00A23V2200/324A23V2250/21A23V2300/14A23V2300/44Y02P10/122
Inventor 胡寅道杨桂芹王志标
Owner 安徽九鑫药业有限公司