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A kind of functional wound-protecting liquid dressing and its preparation method

A liquid dressing, a functional technology, applied in bandages, medical science, etc., can solve the problems of dressings with large pores, opaque dressings, and limited application range, and achieve the effect of reasonable dressing formula, strong bactericidal performance, and good therapeutic effect

Active Publication Date: 2019-10-29
海南一鸿实业发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, some dressings require external fixation materials due to poor adhesion; dressings are generally opaque, making it difficult to observe the wound surface; dressings have large pores, and wound granulation tissue is easy to grow in, making it difficult to remove the membrane and susceptible to bacterial contamination
[0006] From the hospital's point of view, the clinical application of traditional dressings is limited because they do not have the functions of treatment and repair.

Method used

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  • A kind of functional wound-protecting liquid dressing and its preparation method
  • A kind of functional wound-protecting liquid dressing and its preparation method
  • A kind of functional wound-protecting liquid dressing and its preparation method

Examples

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Effect test

Embodiment 1

[0035] A functional wound-protecting liquid dressing, which contains 0.26% of solid raw materials by mass percentage, and the balance is water, wherein the solid raw materials include the following components: 23% of chitosan quaternary ammonium salt, organic silicon quaternary 50% of ammonium salt, 19% of double-chain quaternary ammonium salt, 6% of sodium hyaluronate (molecular weight is 50kDa), 2% of vitamin B12, and the sum of each component of the solid material is 100%.

[0036] The preparation method of described functional wound-protecting liquid dressing comprises the following steps:

[0037] 1) Dissolving the organosilicon quaternary ammonium salt in water to form an organosilicon quaternary ammonium salt solution with a mass concentration of 6%. After dissolving sodium hyaluronate and vitamin B12 in water, adjust the pH to 5.0 and the temperature to 35°C.

[0038] 2) Add an appropriate amount of water into the mixing tank, set the stirring speed of the mixer to 25 ...

Embodiment 2

[0043] A functional wound-protecting liquid dressing, which contains 0.5% of solid raw materials by mass percentage, and the balance is water, wherein the solid raw materials include the following components: 65% of chitosan quaternary ammonium salt, organic silicon quaternary 18% of ammonium salt, 15% of double-chain quaternary ammonium salt, 1% of sodium hyaluronate (molecular weight: 2000kDa), 1% of vitamin B12, and the sum of each component of the solid material is 100%.

[0044] The preparation method of described functional wound-protecting liquid dressing comprises the following steps:

[0045] 1) Dissolving the organosilicon quaternary ammonium salt in water to form an organosilicon quaternary ammonium salt solution with a mass concentration of 6%. After dissolving sodium hyaluronate and vitamin B12 in water, adjust the pH to 5.0 and the temperature to 35°C.

[0046] 2) Add water into the mixing tank, set the stirring speed of the mixer to 25 rpm, first add chitosan qu...

Embodiment 3

[0051] A functional wound-protecting liquid dressing, which contains 0.3% of solid raw materials in terms of mass percentage, and the balance is water, wherein the solid raw materials include the following components: 27.4% of chitosan quaternary ammonium salt, organic silicon quaternary 20% of ammonium salt, 46% of double-chain quaternary ammonium salt, 6% of sodium hyaluronate (molecular weight: 100kDa), 0.6% of vitamin B12, and the sum of each component of the solid material is 100%.

[0052] The preparation method of described functional wound-protecting liquid dressing comprises the following steps:

[0053] 1) Dissolving the organosilicon quaternary ammonium salt in water to form an organosilicon quaternary ammonium salt solution with a mass concentration of 6%. After dissolving sodium hyaluronate and vitamin B12 in water, adjust the pH to 5.0 and the temperature to 35°C.

[0054] 2) Add water into the mixing tank, set the stirring speed of the mixer to 25 rpm, first add...

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Abstract

The invention provides a functional wound-protecting liquid dressing. The functional wound-protecting liquid dressing comprises 23-65% of chitosan quaternary ammonium salt, 18-50% of organosilicon quaternary ammonium salt, 15-46% of double-chain quaternary ammonium salt, 1.6% of sodium hyaluronate and 0.6-2% of vitamin B12. The liquid dressing of the invention is a spray type molecular-level invisible dressing reasonable in formula, and the components of the dressing are fused with each other; and the functional wound-protecting liquid dressing of the invention can significantly improve curative effect, reduce the pain degrees of patients, decrease the changing frequency of the dressing and shorten curing time, has obvious advantages and is worthy of clinical application.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a functional wound-protecting liquid dressing and a preparation method thereof. Background technique [0002] Infection is the most serious interference factor in the wound healing process, mainly manifested in destroying the remaining epithelial tissue and delaying the healing time. When sepsis occurs, epithelial growth can stop. The so-called "sepsis" refers to the proliferation of different microorganisms that invade the wound and produce harmful toxic substances. In severe cases, it can cause systemic poisoning reactions and endanger life. Inflammatory response is the basis of wound healing, but excessive inflammatory response will lead to local tissue cell necrosis, and necrotic tissue is a factor that hinders wound healing, and if it is not controlled in time, it may lead to systemic infection, which will make the wound more severe Difficulty in healing, even lif...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L26/00
CPCA61L26/00A61L26/0023A61L26/0066A61L26/0076A61L2300/208A61L2300/224A61L2300/232A61L2300/236A61L2300/404A61L2300/412A61L2300/45C08L5/08
Inventor 王虹韵陈震
Owner 海南一鸿实业发展有限公司
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