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Full-automatic biochip workstation and detection method thereof

A biochip and technology to be detected, applied in biochemical equipment and methods, microbial measurement/inspection, biomass post-processing, etc., can solve problems such as no record of nucleic acid amplification and hybridization integrated instrument, and achieve stable detection results Reliable, automatic operation, saving operation steps

Pending Publication Date: 2018-12-21
ACADEMY OF MILITARY MEDICAL SCI
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there is no record about the all-in-one instrument for nucleic acid amplification and hybridization

Method used

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  • Full-automatic biochip workstation and detection method thereof
  • Full-automatic biochip workstation and detection method thereof
  • Full-automatic biochip workstation and detection method thereof

Examples

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Embodiment Construction

[0067] The technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings and specific embodiments, but those skilled in the art will understand that the embodiments described below are some of the embodiments of the present invention, rather than all of them. It is only used to illustrate the present invention and should not be construed as limiting the scope of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention. Those who do not indicate the specific conditions in the examples are carried out according to the conventional conditions or the conditions suggested by the manufacturer. The reagents or instruments used were not indicated by the manufacturer, and they were all conventional products that could be purchased from th...

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Abstract

The invention relates to the field of biochip detection equipment, in particular to a full-automatic biochip workstation and a detection method thereof. The full-automatic biochip detection device comprises a cavity for bearing a test tube bottle, a liquid storage device, a pumping device, an imaging device and a data processing device, wherein the test tube bottle is used for accommodating a to-be-detected sample and a biochip, and the cavity has a temperature control function; the liquid storage device is used for storing a liquid; the pumping device is used for pumping the liquid in the liquid storage device to the test tube bottle and is in fluid communication with a skimming needle which injects a mixed liquid into the test tube bottle; the imaging device is used for monitoring the state of the chip in the test tube bottle; and the data processing device is used for acquiring a hybrid result based on information of the biochip state acquired on the basis of the imaging device. Thebiochip workstation provided by the invention outputs biochip reaction and detection results integrally, so that the processing efficiency of samples is improved, the manpower is saved and the resultis more stable and reliable.

Description

technical field [0001] The invention relates to the field of chip hybridization devices, in particular to a fully automatic biological chip workstation and a detection method thereof. Background technique [0002] Biochip hybridization refers to the reaction of protein, DNA or RNA samples isolated from biological samples with biochips, and the sequence information of the samples is obtained from the probe array immobilized on the chip. Since the fluorescence background of the glass slide itself is very low, the method of fluorescent labeling can be used to detect and analyze the biochip, and it has the advantages of rapidity, accuracy and safety. Furthermore, multiple fluorescein labels can be used to analyze multiple biological samples at once. [0003] The following patents are mainly disclosed about the equipment for biochip hybridization: [0004] The application number is 201620379820.0, which discloses a biochip hybridization device, which is characterized in that it...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/34C12Q1/6837
CPCC12Q1/6837C12Q2565/501G01N21/0332G01N21/253G01N21/6452G01N21/76G01N35/10B01L3/502715B01L3/50273B01L3/502738B01L7/00B01L2300/0819B01L2300/1805B01L2300/1894B01L2400/0478B01L2400/0666G01N33/56983
Inventor 王升启荣振肖瑞王封
Owner ACADEMY OF MILITARY MEDICAL SCI