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Image reconstruction method of optimized photoacoustic tomography based on full matrix filter and time reversal operator

A time-reversal, photoacoustic tomography technology, applied in diagnosis, diagnostic recording/measurement, medical science, etc., can solve the problems of narrow imaging area, low resolution, and inability to make full use of photoacoustic data.

Active Publication Date: 2021-04-20
NANJING UNIV
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  • Abstract
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  • Application Information

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Problems solved by technology

For example, the method proposed by people to use correlation matrix filtering to improve the quality of photoacoustic imaging in scattering media [2], however, this method has limitations such as narrow imaging area and low resolution because it cannot make full use of the detected photoacoustic data

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  • Image reconstruction method of optimized photoacoustic tomography based on full matrix filter and time reversal operator
  • Image reconstruction method of optimized photoacoustic tomography based on full matrix filter and time reversal operator
  • Image reconstruction method of optimized photoacoustic tomography based on full matrix filter and time reversal operator

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Embodiment Construction

[0078] The present invention will be further described below in conjunction with the accompanying drawings.

[0079] Such as figure 1 Shown is a schematic diagram of the principle of a photoacoustic tomography image reconstruction method based on matrix filtering and time-reversal operators, taking the imaging of a small steel ball behind the scattering layer as an example, including the following steps.

[0080] Step 1: Arrange 40 small steel balls with a diameter of 0.8 mm randomly and irregularly as a random scattering layer, and place them between the ultrasonic transducer and the target area. Due to the irregular distribution of the scatterers, the received photoacoustic signal not only includes the direct wave from the imaging target, but also includes the scattered wave component after multiple scattering by the scattering layer. The scattering layer is used to generate interference signals. Four small steel balls with a diameter of 0.8 mm were placed behind the scatt...

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Abstract

The invention discloses an image reconstruction method of photoacoustic tomography based on full matrix filtering and time reversal operator. Firstly, an information matrix is ​​constructed according to photoacoustic signals received by an ultrasonic transducer array, and the information matrix includes both Contains the information of the direct wave, and also contains the information of the scattered wave causing interference; then, according to the inverse diagonal property unique to the direct wave part, through operations such as matrix 45° rotation, matrix filtering, and matrix 45° reverse rotation restoration, The scattered wave component in the information matrix can be filtered out; finally, using the time reversal operator, the spatial distribution image of the intensity of the sound wave emitted by the light absorber can be obtained from the filtered information matrix. The method proposed by the invention can effectively filter out the interference of scattered waves, and at the same time completely retain the effective detection information, thereby effectively improving the accuracy of photoacoustic image reconstruction in the scattering medium and after the scattering medium, and has high usability and wide applicability.

Description

technical field [0001] The invention relates to an image reconstruction method of optimized photoacoustic tomography based on full matrix filter and time reversal operator, which belongs to photoacoustic tomography technology. Background technique [0002] As a non-invasive biomedical imaging technology, photoacoustic tomography has developed rapidly in recent years. Photoacoustic tomography not only has the advantages of high resolution of deep tissue by acoustic methods, but also has the advantages of optical methods in functional imaging, molecular imaging and imaging contrast [1]. [0003] However, photoacoustic tomography is usually suitable for media with uniform acoustic properties, and the imaging of scattering media is still a major problem for photoacoustic imaging technology. In the scattering medium, the received photoacoustic signal not only includes the direct wave from the imaging target, but also includes the scattered wave component after multiple scatterin...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00
CPCA61B5/0095A61B5/7225
Inventor 陶超芮纬刘晓峻
Owner NANJING UNIV