Composition for protecting the retina of eyes and relieving asthenopia and antioxidation

A technology that relieves visual fatigue and protects the eyes. It is applied in the direction of active ingredients of hydroxyl compounds, drug combinations, and plant raw materials. It can solve problems such as poor visual fatigue and damage to the retina, and achieve the goal of preventing blue light damage, preventing retinal damage, and low calorie. Effect

Inactive Publication Date: 2019-01-25
杭州上医御本医药保健品科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Most of the eye protection products currently on the market for protecting vision are a single combination of blueb...

Method used

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  • Composition for protecting the retina of eyes and relieving asthenopia and antioxidation
  • Composition for protecting the retina of eyes and relieving asthenopia and antioxidation
  • Composition for protecting the retina of eyes and relieving asthenopia and antioxidation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A composition for protecting eye retina, relieving visual fatigue and anti-oxidation, mainly composed of the following raw materials in parts by weight:

[0029]

[0030] The number average molecular weight of (3R,3'R)-dihydroxy-β-carotene is 568.88g / mol, the moisture content is ≤5.0%; the number average molecular weight of lactose is 342.3g / mol; the DE value of maltodextrin is 13 %; The composition is a tablet.

[0031] To prepare tablets:

[0032] Take D-mannitol, lactose, blueberry powder, maltodextrin, black wolfberry powder, β-carotene, magnesium stearate, lutein ester and (3R,3'R)-dihydroxy-β according to the raw material formula -Carotene, mixed evenly, granulated with 80% ethanol, dried, finally added with magnesium stearate, mixed evenly, compressed into tablets, film-coated, promptly prepared into tablets.

[0033] Table 1 Human experiment results

[0034]

Embodiment 2

[0036] A composition for protecting eye retina, relieving visual fatigue and anti-oxidation, mainly composed of the following raw materials in parts by weight:

[0037]

[0038] The number average molecular weight of (3R,3'R)-dihydroxy-β-carotene is 568.88g / mol, the moisture content is ≤5.0%; the number average molecular weight of lactose is 342.3g / mol; the DE value of maltodextrin is 16 %; The composition is a tablet.

[0039] To prepare tablets:

[0040] Take D-mannitol, lactose, blueberry powder, maltodextrin, black wolfberry powder, β-carotene, magnesium stearate, lutein ester and (3R,3'R)-dihydroxy-β according to the raw material formula -Carotene, mixed evenly, granulated with 80% ethanol, dried, finally added with magnesium stearate, mixed evenly, compressed into tablets, film-coated, promptly prepared into tablets.

[0041] Table 2 Human experiment results

[0042]

Embodiment 3

[0044] A composition for protecting eye retina, relieving visual fatigue and anti-oxidation, mainly composed of the following raw materials in parts by weight:

[0045]

[0046]

[0047] The number average molecular weight of (3R,3'R)-dihydroxy-β-carotene is 568.88g / mol, the moisture content is ≤5.0%; the number average molecular weight of lactose is 342.3g / mol; the DE value of maltodextrin is 17 %; The composition is a tablet.

[0048] To prepare tablets:

[0049] Take D-mannitol, lactose, blueberry powder, maltodextrin, black wolfberry powder, β-carotene, magnesium stearate, lutein ester and (3R,3'R)-dihydroxy-β according to the raw material formula -Carotene, mixed evenly, granulated with 80% ethanol, dried, finally added with magnesium stearate, mixed evenly, compressed into tablets, film-coated, promptly prepared into tablets.

[0050] Table 3 Human experiment results

[0051]

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Abstract

The invention discloses a composition for protecting the retina of eyes and relieving asthenopia and antioxidation, which is mainly composed of the following raw materials in parts by weight: 420 to 430 parts by weight of D-mannitol, 415 to 425 parts by weight of lactose, 90 to 110 parts of blueberry powder, 15 to 25 parts by weight of maltodextrin, 2 to 100 parts of black wolfberry powder, 0.2 to0.5 part by weight of beta-carotene, 10 to 20 parts by weight of magnesium stearate, 1 to 6 parts by weight of lutein ester and 0.5 to 2 parts by weight of (3R, 3'R)-Dihydroxy group-beta-carotene. The composition of the invention has the effects of preventing blue light damage to the retina, relieving asthenopia and resisting oxidation, beta-carotene has the function of tonifying liver and improving eyesight, lutein and (3R, 3'R)-Dihydroxy group-beta-carotene concentrates in macular area of retina through synergistic effect. Macular pigment has the function of preventing blue light damage toretina and relieving asthenopia.

Description

technical field [0001] The invention relates to an ophthalmic composition, in particular to a composition for protecting eye retina, relieving visual fatigue and anti-oxidation. Background technique [0002] With the popularization of electronic products such as smart phones and tablet computers, the blue light emitted by electronic products is more and more harmful to the eyes. Blue light can cause visual fatigue, dry eye syndrome, damage the retina and lens, seriously threaten the health of the fundus, and even induce blindness. [0003] Most of the eye protection products currently on the market are a single combination of blueberry and lutein, which is not effective in preventing blue light from damaging the retina and relieving visual fatigue. Contents of the invention [0004] In view of the above shortcomings, the object of the present invention is to provide a composition that can prevent blue light from damaging the retina, protect the retina of the eye, relieve ...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P27/02A61P27/10A61K31/7016A61K31/23A61K31/045A61K31/015
CPCA61K31/015A61K31/045A61K31/23A61K31/7016A61K36/45A61K36/815A61P27/02A61P27/10A61K2300/00
Inventor 潘群红
Owner 杭州上医御本医药保健品科技开发有限公司
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