The invention discloses a manufacturing method of a spectacle lens with meshes. The method comprises the following steps of cutting treatment, quality inspection, cleaning, drying, surface hardness enhancing, first AR film plating, second AR film plating, convex surface film coating, laser drilling, first AF film plating, surface inspection, drilling inspection and packaging. According to the manufacturing method of the spectacle lens with the meshes, laser drilling is conducted on the lens through laser drilling equipment, the produced lens can cut off and eliminate disordered light generated by the phenomena such as reflection and interference, damage of high light to eyes is avoided, eye fatigue is relieved, a good eye protection effect is achieved, an object can be more obvious, and the visual effect is improved; by means of surface hardness enhancing, the surface hardness of a matrix of the lens is enhanced, and scratches are not likely to appear; by means of first AR film plating and second AR film plating, the light transmittance of the lens is enhanced on the two surfaces, and the visual effect is further improved.