Method for preparing n-butyric acid from poly 3-hydroxybutyrate

A technology of hydroxybutyrate and n-butyric acid, applied in the preparation of carboxylate/lactone, preparation of carboxylate, chemical instruments and methods, etc., can solve the problems of high separation cost, environmental hazards, low yield and the like

Inactive Publication Date: 2019-01-25
DONGGUAN UNIV OF TECH
View PDF1 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the defects and deficiencies of high separation cost, low yield and harm to the environment in the production method of n-butyric acid in the prior art, and to provide a method for preparing n-butyric acid by using poly 3-hydroxybutyrate

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for preparing n-butyric acid from poly 3-hydroxybutyrate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A method for preparing n-butyric acid with poly-3-hydroxybutyrate, said method is as follows:

[0023] Put 5 g of poly-3-hydroxybutyrate in a 300 mL high-temperature and high-pressure reactor, pass through hydrogen to remove the air in the reactor, and keep the pressure of hydrogen at 4 MPa, and keep the reactor secret. Turn on the mechanical stirring, control the mechanical stirring speed to 1000 rpm, raise the temperature to 200 °C at 4 °C / min, and react at 200 °C for 24 h. After the reaction, cool down and put it at room temperature, poly 3-hydroxybutyrate is completely converted, and obtain a liquid product based on n-butyric acid (see figure 1 ). The yield of n-butyric acid detected by gas chromatography quantitative analysis is 97%, and the purity of n-butyric acid in the liquid product is 98%.

Embodiment 2

[0025] A method for preparing n-butyric acid with poly-3-hydroxybutyrate, said method is as follows:

[0026] Put 5 g of poly-3-hydroxybutyrate in a 300 mL high-temperature and high-pressure reactor, pass through hydrogen to remove the air in the reactor, and keep the pressure of hydrogen at 5 MPa, and keep the reactor secret. Turn on the mechanical stirring, control the mechanical stirring speed to 800 rpm, raise the temperature to 210 °C at 4 °C / min, and react at a temperature of 210 °C for 18 h. After the reaction, the temperature was lowered and cooled to room temperature, the poly-3-hydroxybutyrate was completely converted, and a liquid product mainly composed of n-butyric acid was obtained. The yield of n-butyric acid detected by gas chromatography quantitative analysis was 95%, and the purity of n-butyric acid in the liquid product was 97%.

Embodiment 3

[0028] A method for preparing n-butyric acid with poly-3-hydroxybutyrate, said method is as follows:

[0029] Put 5 g of poly-3-hydroxybutyrate in a 300 mL high-temperature and high-pressure reactor, pass through hydrogen to remove the air in the reactor, and keep the pressure of hydrogen at 3 MPa, and keep the reactor secret. Turn on the mechanical stirring, control the mechanical stirring speed to 800 rpm, raise the temperature to 220 °C at 4 °C / min, and react at 220 °C for 12 h. After the reaction, the temperature was lowered and cooled to room temperature to obtain a liquid product mainly composed of n-butyric acid.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a method for preparing n-butyric acid from poly 3-hydroxybutyrate. The method comprises the following steps that poly 3-hydroxybutyrate is put into a sealed device; hydrogen gas is introduced for eliminating air; after the pressure of initial hydrogen gas is 2 to 6 MPa, stirring reaction is performed for 6 to 36h at 190 to 240 DEG C; the n-butyric acid is obtained. The preparation method provided by the invention has the advantages that catalysts and reaction catalysts are not needed; under the hydrogen gas atmosphere condition, the poly 3-hydroxybutyrate is convertedinto the n-butyric acid through one-step reaction; the conversion rate of the 3-hydroxybutyrate is 100 percent; the yield of the n-butyric acid reaches up to 97 percent; the purity of the n-butyric acid in the obtained liquid product reaches up to 98 percent; the additional continuous separation process of the obtained n-butyric acid product is not needed.

Description

technical field [0001] The invention belongs to the field of comprehensive utilization of poly-3-hydroxybutyrate, and in particular relates to a method for preparing n-butyric acid by utilizing poly-3-hydroxybutyrate. Background technique [0002] The development of renewable biomass feedstocks to replace depleted petrochemical resources for the production of chemicals has attracted widespread attention. Poly 3-hydroxybutyrate is a kind of intracellular polyester synthesized by many microorganisms, and it mainly exists as a storage material of carbon source and energy in microorganisms. Poly(3-hydroxybutyrate) can be produced industrially on a large scale through microbial fermentation, and has become an important renewable biomass resource. [0003] N-butyric acid is an important organic chemical, such as being widely used in the synthesis of perfumes, as a raw material for fine chemical products in the synthesis of butyrates and cellulose butyrates. The existing industri...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07C53/124C07C51/09
CPCC07C51/09C07C53/124C08G63/06C07C51/377
Inventor 康世民张航李杰泰李志林徐勇军孙成华洪南龙
Owner DONGGUAN UNIV OF TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap