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Yixinshu concentrated pill and preparation method thereof

A technology that concentrates pills and relieves the heart, and is used in pill delivery, pharmaceutical formulations, cardiovascular system diseases, etc.

Inactive Publication Date: 2019-02-01
GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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  • Yixinshu concentrated pill and preparation method thereof
  • Yixinshu concentrated pill and preparation method thereof
  • Yixinshu concentrated pill and preparation method thereof

Examples

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Embodiment 1

[0062] Prescription: 300g ginseng, 300g Ophiopogon japonicus, 200g schisandra, 300g astragalus, 400g salvia, 200g Chuanxiong, 300g hawthorn

[0063] Preparation method: Ginseng is crushed to obtain fine ginseng powder, and set aside; Schisandra chinensis and Salvia miltiorrhiza are extracted twice with 80% ethanol under reflux, the obtained extracts are filtered, combined, concentrated under reduced pressure to a density of 1.15-1.2 to obtain alcoholic extract A: Decoct Ophiopogon japonicus, Radix Astragali, Rhizoma Chuanxiong and Hawthorn with water twice, combine the decoctions, filter, concentrate the filtrate to 10% of the original volume, add 95% ethanol, stir well, let stand overnight, filter Precipitate, filtrate recovered ethanol and concentrated to a phase density of 1.15 to 1.2 to obtain extract B; ginseng fine powder, extract A and extract B were combined, microwave dried to make granules, and the granules were crushed into fine powder, adding sucrose, Micropowder s...

Embodiment 2

[0065] Prescription: Ginseng 250g, Ophiopogon japonicus 250g, Schisandra 250g, Astragalus 350g, Salvia miltiorrhiza 350g, Chuanxiong 250g, Hawthorn 350g

[0066] Preparation method: Ginseng is crushed to obtain fine ginseng powder, and set aside; Schisandra chinensis and Salvia miltiorrhiza are extracted twice with 70% ethanol under reflux, and the obtained extracts are filtered, combined, concentrated under reduced pressure to a density of 1.15-1.2 to obtain alcoholic extract A: Decoct Ophiopogon japonicus, Radix Astragali, Rhizoma Chuanxiong and Hawthorn with water twice, combine the decoctions, filter, concentrate the filtrate to 12% of the original volume, add 95% ethanol, stir well, let stand overnight, filter Precipitate, filtrate recovered ethanol and concentrated to a phase density of 1.15 to 1.2 to obtain extract B; ginseng fine powder, extract A and extract B were combined, microwave dried to make granules, and the granules were crushed into fine powder, adding sucros...

Embodiment 3

[0068] Prescription: Ginseng 350g, Ophiopogon japonicus 350g, Schisandra 250g, Astragalus 350g, Salvia miltiorrhiza 450g, Chuanxiong 250g, Hawthorn 350g

[0069] Preparation method: Ginseng is crushed to obtain fine ginseng powder, and set aside; Schisandra chinensis and Salvia miltiorrhiza are extracted twice with 85% ethanol under reflux, the obtained extracts are filtered, combined, concentrated under reduced pressure to a density of 1.15-1.2 to obtain alcoholic extract A: Decoct Ophiopogon japonicus, Radix Astragali, Rhizoma Chuanxiong and Hawthorn with water twice, combine the decoctions, filter, concentrate the filtrate to 10% of the original volume, add 95% ethanol, stir well, let stand overnight, filter Precipitate, filtrate recovered ethanol and concentrated to a phase density of 1.15 to 1.2 to obtain extract B; ginseng fine powder, extract A and extract B were combined, microwave dried to make granules, and the granules were crushed into fine powder, adding sucrose, ...

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Abstract

The invention relates to a Yixinshu concentrated pill and a preparation method thereof. Specifically, the Yixinshu concentrated pill is prepared by extraction of ginseng, radix ophiopogonis, Schisandra chinensis, radix astragali, Salvia miltiorrhiza, Ligusticum wallichii and hawthorn as the raw materials. The Yixinshu concentrated by the method can effectively solve the shortcomings in the prior art, and the new Yixinshu preparation provided by the invention has the advantages of easy dissolution and absorption, convenient preservation and oral taking, and remarkable therapeutic effect.

Description

technical field [0001] The invention relates to a Yixinshu concentrated pill and a preparation method thereof, belonging to the technical field of traditional Chinese medicines. Background technique [0002] The prescription of Yixinshu Capsules is made from the ancient prescription "Shengmaiyin" plus flavored blood-activating medicine, which treats both symptoms and root causes. "Shengmai Decoction" is a commonly used basic prescription for the treatment of chest pain, and Shengmai Decoction has been reported in many literatures in the clinical research of coronary heart disease with significant curative effect. Yixin Capsules belong to the national essential medicines (2004), and also belong to the Class B of Chinese patent medicines in the 2004 edition of the "Basic Medical Insurance and Work Injury Insurance Drug Catalog". [0003] Concentrated pills are the product of the combination of traditional Chinese medicine and modern technology, which not only reflects the adv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/20A61K47/38A61P9/10
CPCA61K36/258A61K9/2054A61K36/236A61K36/481A61K36/537A61K36/57A61K36/734A61K36/79A61K36/8968A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61P9/10A61K2300/00
Inventor 安怀略
Owner GUIZHOU XINBANG PHARMACEUTICAL CO LTD