NMN-containing (nicotinamide mononucleotide-containing) composition and preparation to improve climacteric symptoms and their preparation methods and applications

A composition and symptom technology, applied in the field of medicine and health care, can solve the problems of excessive endometrial hyperplasia, uterine bleeding, and large toxic and side effects, and achieve the effects of easy large-scale production, low production cost, and improvement of menopausal symptoms

Inactive Publication Date: 2019-02-19
HOBOOMLIFE BIO TECH SHENZHEN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment method of Western medicine is to use artificially synthesized estrogens, such as diethylstilbestrol, nylestriol, ethinylestradiol, etc., but long-term use of these artificially synthesized estrogens can cause excessive hyperplasia of the endometrium, uterine bleeding, and even cause cervical cancer. , breast cancer, the above-mentioned treatment methods have relatively large toxic and side effects

Method used

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  • NMN-containing (nicotinamide mononucleotide-containing) composition and preparation to improve climacteric symptoms and their preparation methods and applications
  • NMN-containing (nicotinamide mononucleotide-containing) composition and preparation to improve climacteric symptoms and their preparation methods and applications

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] (1) Raw materials: 5 parts by weight of NMN, 5 parts by weight of Epimedium secondary aglycone, 5 parts by weight of chondroitin sulfate, 5 parts by weight of ursodeoxycholic acid, 5 parts by weight of bird's nest acid, 5 parts by weight of parts of s-adenosylmethionine, 5 parts of Zhiyuan, 5 parts of DHA, and 5 parts of γ-aminobutyric acid.

[0043] (2) Accessories:

[0044] Including the following parts by weight: 15 parts of Shichangpu, 8 parts of Radix Paeoniae Rubra, 30 parts of Baiziren, 20 parts of theanine, 20 parts of Anemarrhena, 10 parts of Centella asiatica, 15 parts of ginseng leaves, 5 parts of Jiji, 10 parts of silver thread grass, 5 dragon boat flowers; accessories also include parkin complex ester, fumaric acid, fumed silica.

[0045] (3) Preparation method:

[0046] First, pass the dried raw and auxiliary materials through a 30-80 mesh sieve, so that the particle size distribution is uniform, the fluidity is better, and the raw and auxiliary material...

Embodiment 2

[0049] (1) Raw materials: 10 parts by weight of NMN, 1 part by weight of Epimedium secondary aglycone, 10 parts by weight of chondroitin sulfate, 1 part by weight of ursodeoxycholic acid, 10 parts by weight of bird's nest acid, 1 part by weight of parts of s-adenosylmethionine, 10 parts by weight of Zhiyuan, 1 part by weight of DHA, and γ-aminobutyric acid of 10 parts by weight

[0050] (2) Accessories:

[0051] Including the following parts by weight: 4 parts of Shichangpu, 20 parts of Radix Paeoniae Rubra, 20 parts of Baiziren, 30 parts of theanine, 10 parts of Zhimu, 20 parts of Centella asiatica, 4 parts of ginseng leaves, 12 parts of Jiji, 5 parts Silver thread grass, 10 parts of dragon boat flower, 5 parts of lingxiaohua, 10 parts of wheat bottle grass, 4 parts of North China columbine, 8 parts of deergrass, 3 parts of Spatholobus yunnanensis, 20 parts of medlar, 7 parts of rehmannia, 15 parts Angelica, 4 parts of Cuscuta, 15 parts of Anemarrhena, 7 parts of Morinda off...

Embodiment 3

[0059] (1) Raw materials: 1 weight part of NMN, 10 weight parts of Epimedium secondary aglycon, 1 weight part of chondroitin sulfate, 10 weight parts of ursodeoxycholic acid, 1 weight part of sialic acid, 10 weight parts part of s-adenosylmethionine, 1 part by weight of Zhiyuan, 10 parts by weight of DHA, and 1 part by weight of γ-aminobutyric acid.

[0060] (2) Accessories:

[0061] Including the following auxiliary materials in parts by weight: 7 parts of Shichangpu, 15 parts of Radix Paeoniae Rubra, 25 parts of Baiziren, 25 parts of theanine, 15 parts of Anemarrhena, 15 parts of Centella asiatica, 10 parts of ginseng leaves, 10 parts of Jiji, 7 parts of silvergrass, 7 parts of dragon boat flower, 7 parts of lingxiaohua, 7 parts of wheat bottle grass, 6 parts of North China columbine, 6 parts of deergrass, 4 parts of Spatholobus, 15 parts of medlar, 12 parts of rehmannia, 10 parts of angelica, 10 parts of dodder, 10 parts of Anemarrhena.

[0062] The excipients also includ...

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Abstract

The invention discloses NADH-containing (nicotinamide mononucleotide-containing) composition and preparation to improve climacteric symptoms and their preparation methods and applications and relatesto the field of medicine and health. The composition includes, by weight, 1-10 parts of NMN, 1-10 parts of secondary anhydroicaritin, 1-10 parts of chondroitin sulfate, 1-10 parts of ursodesoxycholicacid, 1-10 parts of sialic acid, 1-10 parts of S-adenosyl methionine, 1-10 parts of polygala root, 1-10 parts of DHA (docosahexaenoic acid), and 1-10 parts of gamma-aminobutyric acid. The components of the composition are in suitable ratio and can coact to all-directionally improve climacteric symptoms safely with no side effects. The preparation method of the preparation has a simple process flow, short process time and zero byproducts, is low in production cost and is easy to apply to large-scale production.

Description

technical field [0001] The invention relates to the fields of medicine and health care, in particular to a composition containing NMN for improving menopausal symptoms, a preparation, a preparation method and application thereof. Background technique [0002] Menopausal syndrome, also known as perimenopausal syndrome, is a series of syndromes characterized by autonomic nervous system dysfunction and neuropsychological symptoms caused by fluctuations or decreases in sex hormones before and after menopause. Menopause can be divided into natural menopause and artificial menopause. Natural menopause means that the follicles in the ovary are exhausted, or the remaining follicles lose their response to gonadotropins, and the follicles no longer develop and secrete estrogen, and cannot stimulate the growth of the endometrium, leading to menopause. Artificial menopause refers to the surgical removal of both ovaries or the use of other methods to stop ovarian function, such as radia...

Claims

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Application Information

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IPC IPC(8): A61K36/69A61P15/12A61K31/737A61K31/575A61K31/706A61K31/352A61K31/197A61K31/7012A61K31/7076A61K31/201
CPCA61K31/197A61K31/201A61K31/352A61K31/575A61K31/7012A61K31/706A61K31/7076A61K31/737A61K36/69A61P15/12A61K2300/00
Inventor 刘喜元张慧梁倩
Owner HOBOOMLIFE BIO TECH SHENZHEN CO LTD
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