A kind of tripeptide and its preparation method and application

A peptide resin, amino acid technology, applied in the field of peptides, to achieve the effect of anti-aging
CN109369778BActive Publication Date: 2020-11-06INFINITUS (CHINA) CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
INFINITUS (CHINA) CO LTD
Publication Date
2020-11-06

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Abstract

The invention relates to the technical field of polypeptides, in particular to tripeptide and a preparation method and use thereof. The tripeptide FGF has the amino acid sequence of Phe-Gln-Phe, and the preparation method and the use of the tripeptide are provided. Experiments show that FITC fluorescence intensity of FQF high and low dose groups has significant difference, indicating that FQF cansignificantly reduce the intracellular ROS level and play an antioxidant role. The tripeptide can be widely used in the preparation of drugs or foods inhibiting CD38 enzyme activity, or in the preparation of drugs or foods with anti-oxidation and anti-aging effects.
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Description

technical field

[0001] The invention relates to the technical field of polypeptides, in particular to a tripeptide and its preparation method and application. Background technique

[0002] The CD38 enzyme catalytic substrates cyclic adenosine diphosphate-ribose (cADPR), adenosine diphosphate-ribose (ADPR) and nicotinic acid adenosine dinucleotide phosphate (NAADP) can bind to different receptors or channels, thereby participating in the regulation of cell Calcium signal, by acting on the relevant receptor system of the human body, these Ca 2+ Small messenger molecules can regulate the release of intracellular calcium ions and the influx of extracellular calcium ions under physiological conditions, thereby regulating cell functions and life activities. Nicotinamide adenine dinucleotide (NAD + ) as the substrate of Sir2-related enzymes sirtuins and as the molecule connecting nicotinamide phosphoribosyl transferase (Nampt) and SIRT1, has been extensively studied recently, bec...

Claims

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