36results about How to "Reduce ROS levels" patented technology

a preparation g -C 3 N 4 In the method of composite carrier with carbon fiber, a certain amount of nitrogen-containing organic matter is added to the organic reagent, after mixing evenly, electrospinning is carried out, and the product is pre-oxidized and carbonized, and then the product is oxidized to obtain g -C 3 N 4 and carbon fiber composite carrier. Preparation of the present invention g -C 3 N 4 Composite carrier with carbon fiber has the characteristics of simple preparation process, adjustable specific surface area, pore size and surface polarity of the carrier. When applied to immobilized cell fermentation, it has high immobilization efficiency and fermentation stability.

The present invention relates to the active ingredient of A. chinensis, which is characterized in that it comprises oleanolic acid-type triterpenoid saponins and / or phenylacetonitrile glycosides, and the structural formula of the oleanolic acid-type triterpenoid saponins is as follows: The structural formula of phenylacetonitrile glycosides is shown below: . The present invention also provides a preparation method of the active ingredient of the Fructus Arugulae. According to the experiment, the invention finds that the active components of Fructus chinensis have a good protective effect on the oxidative damage of nerve cells NSC34, and can be used for preparing neuroprotective drugs or health care products.

The invention discloses a method for improving the acid stress resistance of T. glabrata, belonging to the field of biological engineering. The present invention constructs a gene deletion mutant strain Cgade12Δ by transforming T. glabrata, measures the intracellular ATP level of the constructed strain, and analyzes the organic acid tolerance of the strain through a plate growth experiment and cell activity. After the deletion of the gene CgADE12 was found, under 0.2% acetic acid stress, the intracellular ATP level of the strain decreased, the growth ability under acetic acid stress increased, and the acetic acid tolerance was enhanced.

The invention discloses a substituted phenyl indoline carbazole derivative and a preparation method and application thereof. Please see the structural formula in formula I, wherein Ar adopts hydroxyphenyl or 3-carboxyl-4-hydroxyphenyl or 3,5-dimethoxy-4-hydroxyphenyl. The substituted phenyl indoline carbazole derivative can obviously lower the ROS level in a leukemia cell and can serve as a candidate compound of an antineoplastic drug and / or an anti-leukemia chemotherapeutic agent and / or a leukemia differentiation inducer.

The invention relates to the application of Prussian blue nanoparticles in the preparation of drugs for preventing, delaying or treating degenerative diseases of the nervous system. The research of the present invention finds that the Prussian blue nanoparticles have remarkable efficacy in preventing, delaying or treating degenerative diseases of the nervous system. The results of cell-level experiments show that Prussian blue nanoparticles can reduce the ROS level in nerve cells stimulated by hydrogen peroxide, and increase the proportion of living cells in nerve cells stimulated by hydrogen peroxide; the results of animal-level experiments show that Prussian blue nanoparticles can significantly Reduce the expression level of oxidative stress markers in the hippocampus of neurodegenerative disease model mice, significantly improve the learning and memory abilities of neurodegenerative disease model mice, and improve motor dysfunction. Moreover, the preparation process of the Prussian blue nanoparticles is simple, easy for mass production, mild reaction conditions, and easy for surface modification.