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Hand disinfection gel and preparation method thereof

A hand disinfection and gel technology, which is applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve problems such as toxic and side effects, achieve less skin irritation, and reduce skin moisture loss , good bactericidal effect

Inactive Publication Date: 2019-03-22
郑州吉尔康消毒制品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Dichlorophenoxychlorophene in the above-mentioned hand sanitizer gel also has toxic and side effects

Method used

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  • Hand disinfection gel and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] The hand sanitizing gel of the present embodiment is made up of each component of following mass percentage:

[0033] 42.4% ethanol, 10% isopropanol, 0.2% thickener, 0.2% emollient, 0.10% pH regulator, and the balance is water.

[0034] Ethanol is edible alcohol whose volume fraction is 95%.

[0035] The thickener is Carbomer 940.

[0036] The pH adjuster is aminomethyl propanol.

[0037] The emollient is a mixture of vitamin E and glycerin, and the mass ratio of vitamin E and glycerin is 1:3.

[0038] The preparation method of the hand sanitizing gel of the present embodiment comprises the following steps:

[0039] 1) Take the formula amount of water, add the formula amount of thickener and beat until the mixture of thickener and water becomes transparent to obtain a thickener solution;

[0040] 2) adding ethanol and an emollient in a formulated amount to the thickener solution in step 1), and stirring to obtain a basic gel matrix;

[0041] 3) Add a formulated amo...

Embodiment 2

[0043] The hand sanitizing gel of the present embodiment is made up of each component of following mass percentage:

[0044] 52.1% ethanol, 5% isopropanol, 0.1% thickener, 0.3% emollient, 0.15% pH regulator, and the balance is water.

[0045] Ethanol is edible alcohol whose volume fraction is 95%.

[0046] The pH adjuster is aminomethyl propanol.

[0047] The thickener is Carbomer 934.

[0048] The emollient is a mixture of vitamin E and glycerin, and the mass ratio of vitamin E and glycerin is 1:5.

[0049] The preparation method of the hand sanitizing gel of the present embodiment comprises the following steps:

[0050] 1) Take the formula amount of water, add the formula amount of thickener and beat until the mixture of thickener and water becomes transparent to obtain a thickener solution;

[0051] 2) adding ethanol and an emollient in a formulated amount to the thickener solution in step 1), and stirring to obtain a basic gel matrix;

[0052] 3) Add a formulated amou...

Embodiment 3

[0054] The hand sanitizing gel of the present embodiment is made up of each component of following mass percentage:

[0055] Ethanol 62.4%, isopropanol 3%, thickener 0.5%, emollient 1.5%, pH regulator 0.15%, and the balance is water.

[0056] Ethanol is edible alcohol whose volume fraction is 95%.

[0057] The thickener is Carbomer 940.

[0058] The emollient is a mixture of glycerol polyether and glycerol, and the mass ratio of glycerol polyether to glycerol is 1:3.

[0059] The pH adjuster is aminomethyl propanol.

[0060] The preparation method of the hand sanitizing gel of the present embodiment comprises the following steps:

[0061] 1) Take the formula amount of water, add the formula amount of thickener and beat until the mixture of thickener and water becomes transparent to obtain a thickener solution;

[0062] 2) adding ethanol and an emollient in a formulated amount to the thickener solution in step 1), and stirring to obtain a basic gel matrix;

[0063] 3) Add a ...

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Abstract

The invention relates to hand disinfection gel and a preparation method thereof, belonging to the technical field of sanitizers. The hand disinfection gel is prepared from the following components bymass percent: 42.4-73.5% of ethanol, 2-10% of isopropyl alcohol, 0.1-0.5% of a thickener, 0.2-2.0% of an emollient, 0.08-0 .18% of a pH adjuster and the balance of water. The ethanol is combined withthe thickener so as to form the gel, and the gel is adjusted to a stable state by means of the pH adjuster; the added emollient can reduce the irritation of the ethanol to the hand skin of a user; dueto the cooperation of all the components, the hand disinfection gel not only has a good sterilizing effect, but is also small in irritation to the skin.

Description

technical field [0001] The invention belongs to the technical field of disinfecting gel, and in particular relates to a hand disinfecting gel and a preparation method thereof. Background technique [0002] Commonly used disinfectants in hand disinfection gels include oxidizing disinfectants, alcohol disinfectants, surfactant disinfectants, and biological disinfectants. Oxidizing disinfectants include peroxide disinfectants, chlorine-containing disinfectants, iodine-containing disinfectants, etc. Alcohol disinfectants include ethanol and isopropanol. Surfactant disinfectants include chlorhexidine and quaternary ammonium disinfectants. Biological disinfectants are mainly living microorganisms. When current hand disinfection gels use volatile alcohols as disinfectants and solvents, ethanol or isopropanol is generally used in consideration of safety and non-toxicity requirements. Ethanol and isopropanol have a dehydrating effect that can coagulate proteins and lead to the de...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/886A61K31/045A61K9/06A61K47/32A61K47/18A61P31/04A61P31/10A61P31/02A61P17/00
CPCA61K9/0014A61K9/06A61K31/045A61K36/886A61K36/896A61K47/18A61K47/32A61P17/00A61P31/02A61P31/04A61P31/10A61K2300/00
Inventor 邝金瑞王秋艳吕素敏
Owner 郑州吉尔康消毒制品有限公司
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