Prognosis evaluation of rehabilitation of patients with ischemic stroke

Abstract

The invention discloses a method for prognosis evaluation of rehabilitation of patients with ischemic stroke. The method particularly relates to the screening of metabolites capable of being used as markers, and the markers can be used for evaluating difference between prognosis of rehabilitation treatment of the patients with ischemic stroke. The method further discloses the use of a reagent forquantitatively detecting the markers in the preparation of a kit for prognosis evaluation of rehabilitation treatment effects of patients with ischemic stroke, and the markers are / is arginine and / or malondialdehyde. By adopting the markers of arginine and malondialdehyde metabolome screened by using the method of the invention, the precise prognosis evaluation and analysis of rehabilitation treatment effects of patients with ischemic stroke can be conducted timely, the rehabilitation treatment period of people with stroke is effectively shortened, and the prediction of the rehabilitation treatment clinical effects of people with stroke can be facilitated.

Description

technical field [0001] The invention belongs to the field of clinical diagnosis and medical treatment, and in particular relates to a prognosis evaluation method for rehabilitation treatment of ischemic stroke population. Background technique [0002] Cerebral stroke, that is, cerebral apoplexy, is an acute or focal brain dysfunction caused by various cerebrovascular diseases, which lasts for more than 24 hours, and has the characteristics of high morbidity, high mortality, and high disability rate. Stroke is divided into two types, ischemic stroke (cerebral infarction, etc.) and hemorrhagic stroke (cerebral hemorrhage, etc.), and ischemic stroke accounts for about 70% of the total number of strokes. Ischemic stroke refers to a cerebrovascular disease in which brain tissue ischemia and hypoxia lead to necrosis and softening to form infarction due to cerebral blood supply disturbance. The main clinical manifestations are hemiplegia, disturbance of consciousness, and cognitiv...

AI Technical Summary

Problems solved by technology

It can be seen from the comparison that there is a large gap between the rehabilitation treatment effect of stroke patients in my country and developed countries, which has a lot to do with the inability to give patients accurate prognosis assessment and more targeted rehabilitation treatment.

In the past, the prediction of functional recovery in stroke patients mostly relied on the experience of clinicians, and there were many uncertainties, and the evaluation of some scales was not completely reliable. For example, different patients with the same scale score had different outcomes.

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