Bifidobacterium pseudocatenulatum CCFM1048, composition, fermented food, application and bacterial agent of bifidobacterium pseudocatenulatum CCFM1048 and preparation method of bacterial agent of bifidobacterium pseudocatenulatum CCFM1048

Abstract

The invention discloses bifidobacterium pseudocatenulatum CCFM1048, a composition, fermented food, application and bacterial agent of the bifidobacterium pseudocatenulatum CCFM1048 and a preparation method of the bacterial agent of the bifidobacterium pseudocatenulatum CCFM1048. The bifidobacterium pseudocatenulatum CCFM1048 can tolerate the gastrointestinal environment of the human body, significantly relieve the rise, caused by the high fat diet, of content of triglyceride in the liver of a mouse with the metabolic syndrome, relieve the weight rise of the mouse with the metabolic syndrome, significantly improve abnormal fasting blood glucose and abnormal oral glucose tolerance of the mouse with the metabolic syndrome, reduce the area under the drug-time curve of glucose tolerance, improve the serum insulin level, significantly relieve the rise, caused by the high fat diet, of content of low density lipoprotein cholesterol in serum and significantly relieve the rise, caused by the high fat diet, of Proteus in the intestinal tract; the bifidobacterium pseudocatenulatum CCFM1048 is used for preparing the medicine composition and the fermented food which relieve the metabolic syndrome and reduce the occurrence of diseases such as the Parkinson disease, intestinal infection and urinary tract and kidney infection and has a quite wide application prospect.

Description

technical field [0001] The invention belongs to the technical field of microbes, and in particular relates to Bifidobacterium pseudosmall chain CCFM1048, its composition, fermented food, use, bacterial agent and preparation method thereof. Background technique [0002] In recent years, with the continuous development of my country's social and economic level, the living standards of the public have continued to improve, the proportion of carbohydrates and fats in the diet structure has increased day by day, and the restrictions of many working conditions have made it easy for people to develop sedentary behavior Habit. These external environmental factors combined with their own genetic factors have jointly led to the continuous increase in the incidence of metabolic syndrome in the Chinese population. According to reports, between 2002 and 2010, the proportion of people over the age of 20 in China suffering from metabolic syndrome rose from 5.4% to 21.3%, an increase of 4 t...

AI Technical Summary

Problems solved by technology

These drugs have a good curative effect on each single risk factor of metabolic syndrome. However, long-term use of drugs has certain side effects. For example, long-term use of metformin can cause irritation to the gastrointestinal tract of some patients and cause discomfort and may affect the patient’s response to vitamin B12. The absorption of rosiglitazone can cause liver function damage and edema, etc.

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