Kit and method for detecting genes related to individualized medication for depression

A kit, depression technology, applied in the direction of DNA / RNA fragments, recombinant DNA technology, etc., can solve the problems of inaccurate prediction, few drugs and genes, and lack of treatment options for patients with refractory depression, so as to achieve comprehensive and accurate detection , time-saving effect
CN110157793APending Publication Date: 2019-08-23广州海思医疗科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
广州海思医疗科技有限公司
Publication Date
2019-08-23

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Abstract

The invention discloses a primer group, a kit and a detection method for detecting genes related to individualized medication for depression. The primer group is selected from nucleotide sequences inSEQ ID NO.1-SEQ ID NO.154. The detection kit covers eight major categories of clinical first-line and second-line antidepressant efficacy-related genes, and relates to drug metabolism, target spots and transporter gene loci, and detection is conducted comprehensively and accurately. Accordingly, aiming at part of patients suffering from treatment-refractory depression, gene detection related to the therapeutic effect of antidepressant synergistic drugs is added, and powerful support is provided for selection of therapeutic schedules of the treatment-refractory depression.
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Description

technical field

[0001] The invention relates to the technical field of gene detection, in particular to a kit and method for detecting genes related to individualized medication for depression. Background technique

[0002] Depression, also known as depressive disorder, is a common mental illness. According to statistics from the World Health Organization, by 2020, depression will become the second leading disease after heart disease. At present, more than 300 million people in the world are suffering from depression. The prevalence rate of depression in China is 6.1%, which is 3 percentage points higher than the global average, and the incidence rate has been increasing year by year in recent years. It is converted according to the incidence rate of 6.1%. , domestic depression patients have reached 90 million.

[0003] At present, the most effective means of treating depression is drug therapy, but it is still in the stage of trial and error, and the efficacy and adverse ...

Claims

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