New process for preparing food-grade 2,6-di-tert-butyl-p-methylphenol

Abstract

The invention belongs to the technical field of organic synthesis technologies, and particularly relates to a new process for preparing food-grade 2,6-di-tert-butyl-p-methylphenol. The process comprises the steps: using p-cresol and isobutylene as reaction raw materials, selecting a solid acid catalyst, and performing an alkylation reaction under the heating condition so as to obtain the product,wherein the solid acid catalyst is cerium sulfate, ammonium ferric sulfate or phosphotungstic acid. According to the preparation process, the reaction yield of 2,6-di-tert-butyl-p-methylphenol which is prepared from cresol and isobutylene can be improved by using the solid acid catalyst, the reaction time is shortened, purification in the later stage is convenient, and the product can reach the food-grade requirement.

Description

technical field [0001] The invention belongs to the technical field of organic synthesis technology, and in particular relates to a new technology for preparing food-grade 2,6-di-tert-butyl-p-cresol. Background technique [0002] The synthesis of traditional 2,6-di-tert-butyl-p-cresol is usually based on p-cresol or recycled monobutylphenol and isobutene as raw materials, with concentrated sulfuric acid or p-toluenesulfonic acid liquid as a catalyst, in an alkylation tank Synthesize 2,6-di-tert-butyl p-cresol, heat the reaction product in a neutralization tank, neutralize excess acid catalyst with saturated sodium carbonate solution, but most conversion efficiencies are relatively low, generally at 70-78 %, the reaction time is relatively long, and there are many by-products, and the liquid acid used in the process needs a large amount of saturated alkali solution to neutralize, which will produce a large amount of waste water, and the production cost is relatively high; in ...

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Problems solved by technology

[0002] The synthesis of traditional 2,6-di-tert-butyl-p-cresol is usually based on p-cresol or recycled monobutylphenol and isobutene as raw materials, with concentrated sulfuric acid or p-toluenesulfonic acid liquid as a catalyst, in an alkylation tank Synthesize 2,6-di-tert-butyl p-cresol, heat the reaction product in a neutralization tank, neutralize excess acid catalyst with saturated sodium carbonate solution, but most conversion efficiencies are relatively low, generally at 70-78 %, the reaction time is relatively long, and there are many by-products, and the liquid acid used in the process needs a large amount of saturated alkali solution to neutralize, which will produce a large amount of waste water, and the production cost is relatively high; in addition, the traditional process uses recrystallization or rectification The process is relatively independent, and the purification effect is generally 98%

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