Method for treating epilepsy by a traditional Chinese medicine composition containing CBD (cannabidiol)

A technology of cannabidiol and composition, which is applied in the field of pharmacy and can solve problems such as ineffective effects and slow effects

Inactive Publication Date: 2019-09-27
DAXINGANLING LINGOBERRY BOREAL BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the shortcomings of the existing traditional Chinese medicine preparations for treating epilepsy, such as ineffective and slow effects, and provide a method for treating epilepsy with a Chinese medicine composition containing cannabidiol, which has a small prescription and a simple preparation method , in which cannabidiol can help control the consumption of GABA neurotransmitters with a calming effect in the brain, can effectively inhibit brain excitement, reduce seizures, and can also help improve the efficacy of other antiepileptic drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The preparation of the traditional Chinese medicine composition in the present invention is based on the parts by weight of raw materials: 30 parts of CBD (plant extract), 55 parts of Gastrodia elata, 25 parts of Bupleurum, 25 parts of antelope horn, 45 parts of Shichangpu, 35 parts of licorice, and 25 parts of ginseng , 22 parts of mother-of-pearl, 8 parts of musk.

[0029] The preparation method comprises the following steps:

[0030] Step 1: Extract and purify 30 parts of industrial hemp according to patent 201910358996.6 and patent 201910358997.0 respectively, to obtain cannabidiol extract for later use;

[0031] The second step: in parts by weight, 55 parts of Gastrodia elata, 25 parts of Bupleurum, 25 parts of antelope horn, 45 parts of Shichangpu, 35 parts of licorice, 25 parts of ginseng, 22 parts of mother of pearl, 8 parts 100% musk, add 15 times the weight of the drug for decoction for 2 hours for the first time, and pour out the decoction;

[0032] Step 3:...

Embodiment 2

[0038] The preparation of the traditional Chinese medicine composition in the present invention is based on the parts by weight of raw materials: 40 parts of CBD (plant extract), 60 parts of Gastrodia elata, 30 parts of Bupleurum, 30 parts of antelope horn, 50 parts of Shichangpu, 40 parts of licorice, and 30 parts of ginseng , 25 parts of mother-of-pearl, 10 parts of musk.

[0039] The preparation method comprises the following steps:

[0040] Step 1: Extract and purify 40 parts of industrial hemp according to patent 201910358996.6 and patent 201910358997.0 respectively, to obtain cannabidiol extract for later use;

[0041] The second step: in parts by weight, 60 parts of Gastrodia elata, 30 parts of Bupleurum, 30 parts of antelope horns, 50 parts of Shichangpu, 40 parts of licorice, 30 parts of ginseng, 25 parts of mother-of-pearl, 10 parts 100% musk, add 13 times the weight of the medicine for the first time and decoct for 3 hours, then pour out the decoction;

[0042] St...

Embodiment 3

[0048] The preparation of the traditional Chinese medicine composition in the present invention is based on the parts by weight of raw materials: 45 parts of CBD (plant extract), 65 parts of Gastrodia elata, 35 parts of Bupleurum, 35 parts of antelope horn, 55 parts of Shichangpu, 45 parts of licorice, and 35 parts of ginseng , 30 parts of mother-of-pearl, 12 parts of musk.

[0049] The preparation method comprises the following steps:

[0050]Step 1: Extract and purify 45 parts of industrial hemp according to patent 201910358996.6 and patent 201910358997.0 respectively, to obtain cannabidiol extract and set aside;

[0051] The second step: in parts by weight, 65 parts of gastrodia elata, 35 parts of Bupleurum bupleurum, 35 parts of antelope horns, 55 parts of iris calamus, 45 parts of licorice, 35 parts of ginseng, 30 parts of mother of pearl, 12 parts of Part of musk mixed, add 11 times the amount of drug weight for the first time to decoct for 2.5 hours, pour out the decoc...

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PUM

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Abstract

The invention belongs to the technical field of pharmacy, and particularly relates to a method for treating epilepsy by a traditional Chinese medicine composition containing CBD (cannabidiol). The method comprises the following steps: firstly, determining composition and components by weight of the traditional Chinese medicine composition, and extracting industrial hemp raw materials from the traditional Chinese medicine composition independently to obtain a high-purity CBD extract; mixing and extracting the rest traditional Chinese medicines and performing decoction three times; mixing decoctions, concentrating the decoctions into thick paste, adding the CBD extract, uniformly stirring the mixture, and performing vacuum drying at low temperature; pulverizing a product, performing sieving to obtain fine powder, adding a wetting agent to prepare a soft material, granulating the soft material, and performing filling to form capsules. According to Provisions for New Drug Approval and The Technical Guidelines for the Acute Toxicity test of traditional Chinese Medicine and Natural Medicine, the traditional Chinese medicine composition containing CBD is subjected to acute toxicity experiment evaluation, safety of the traditional Chinese medicine composition is determined, actual case analysis shows that the traditional Chinese medicine composition has a remarkable effect on epilepsy treatment and is widely applicable to people.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a method for treating epilepsy with a traditional Chinese medicine composition containing cannabidiol. Background technique [0002] Epilepsy is one of the most common diseases in neurology. According to the survey results of relevant departments, there are more than 9 million epileptic patients in my country. Recurrent epilepsy can aggravate brain tissue hypoxia and cause more brain cells to be damaged. The disease is getting worse, so effective prevention and treatment of epilepsy has become an urgent problem to be solved. Most of the commonly used antiepileptic western medicines have side effects such as causing fatigue, lethargy, memory loss, and affecting the intelligence of patients; while surgical treatment of epilepsy, gene therapy, etc. are expensive, risky, and have uncertain curative effects. Compared with modern medicine, traditional Chinese medicine has ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P25/08A61K31/05A61K35/32A61K35/55A61K35/618
CPCA61K31/05A61K35/32A61K35/55A61K35/618A61K36/233A61K36/258A61K36/484A61K36/888A61K36/8988A61P25/08A61K2300/00
Inventor 姚德坤姜彩霞姚航
Owner DAXINGANLING LINGOBERRY BOREAL BIOTECH CO LTD
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