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Traditional Chinese medicine tablet with blood lipid lowering function and preparation method thereof

A traditional Chinese medicine tablet and blood lipid-lowering technology, which is applied to medical preparations containing active ingredients, pharmaceutical formulas, pill delivery, etc., can solve the problems of large dosage, inconvenient taking, and insufficient curative effect, and achieve small content differences, easy transportation and Portable, unbreakable effect

Inactive Publication Date: 2019-10-08
郑州桂仁医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the toxic and side effects of traditional Chinese medicine are relatively small, there are shortcomings such as large dosage, insufficient curative effect and inconvenient taking, which cannot be accepted by consumers.

Method used

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  • Traditional Chinese medicine tablet with blood lipid lowering function and preparation method thereof
  • Traditional Chinese medicine tablet with blood lipid lowering function and preparation method thereof
  • Traditional Chinese medicine tablet with blood lipid lowering function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A traditional Chinese medicine tablet with hypolipidemic function, comprising the following raw materials in parts by weight: 154 parts of red yeast rice powder, 140 parts of Gynostemma pentaphyllum extract, 105 parts of curcumin, 91 parts of tea polyphenols, 126 parts of microcrystalline cellulose, and 59.5 parts of cornstarch parts, 21 parts of low-substituted hydroxypropyl cellulose, and 3.5 parts of magnesium stearate.

[0036] The preparation method of the above-mentioned traditional Chinese medicine tablet with hypolipidemic function, comprises the following steps:

[0037] S1. Mixing granulation: mix red yeast rice powder, Gynostemma pentaphyllum extract, curcumin, tea polyphenols, microcrystalline cellulose and cornstarch, add ethanol solution with a mass concentration of 20%, stir for 20min, mix well and use a sieve mesh For 14-mesh granulator granulation, the ratio of the added ethanol solution to the total mass of raw materials is 0.2:1;

[0038] S2. Drying ...

Embodiment 2

[0042] A traditional Chinese medicine tablet with hypolipidemic function, comprising the following raw materials in parts by weight: 150 parts of red yeast rice powder, 145 parts of Gynostemma pentaphyllum extract, 105 parts of curcumin, 90 parts of tea polyphenols, 130 parts of microcrystalline cellulose, and 55 parts of cornstarch 22.5 parts of low-substituted hydroxypropyl cellulose and 4 parts of magnesium stearate.

[0043]The preparation method of the above-mentioned traditional Chinese medicine tablet with hypolipidemic function, comprises the following steps:

[0044] S1. Mixing granulation: mix red yeast rice powder, Gynostemma pentaphyllum extract, curcumin, tea polyphenols, microcrystalline cellulose and cornstarch, add ethanol solution with a mass concentration of 25%, stir for 20min, and use a sieve mesh after mixing evenly For 14-mesh granulator granulation, the ratio of the added ethanol solution to the total mass of raw materials is 0.25:1;

[0045] S2. Drying...

Embodiment 3

[0049] A traditional Chinese medicine tablet with hypolipidemic function, comprising the following raw materials in parts by weight: 155 parts of red yeast rice powder, 140 parts of Gynostemma pentaphyllum extract, 100 parts of curcumin, 92.5 parts of tea polyphenols, 120 parts of microcrystalline cellulose, and 60 parts of cornstarch 25 parts of low-substituted hydroxypropyl cellulose, 2 parts of magnesium stearate.

[0050] The preparation method of the above-mentioned traditional Chinese medicine tablet with hypolipidemic function, comprises the following steps:

[0051] S1. Mixing granulation: mix red yeast rice powder, Gynostemma pentaphyllum extract, curcumin, tea polyphenols, microcrystalline cellulose and cornstarch, add ethanol solution with a mass concentration of 15%, stir for 15min, mix well and use a sieve mesh For 15-mesh granulator granulation, the ratio of the added ethanol solution to the total mass of raw materials is 0.22:1;

[0052] S2. Drying and sizing: ...

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Abstract

The invention provides a traditional Chinese medicine tablet with the blood lipid lowering function and a preparation method thereof. The traditional Chinese medicine tablet comprises, by weight, 150-160 parts of red koji powder, 135-145 parts of a gynostemma pentaphylla extract, 100-110 parts of curcumin, 90-95 parts of tea polyphenol, 120-130 parts of microcrystalline cellulose, 55-60 parts of corn starch, 20-25 parts of low-substituted hydroxypropyl cellulose and 1-5 parts of magnesium stearate. The red koji powder is compounded with the gynostemma pentaphylla extract, curcumin and tea polyphenol to prepare the traditional Chinese medicine tablet which is easy to be accepted and taken by eaters and can effectively reduce the contents of serum total cholesterol (TC), triglyceride (TG) and high density lipoprotein cholesterol in patients with hyperlipidemia; the traditional Chinese medicine tablet has the advantages of small different in content, accurate specification and measurement, stable content of functional components or iconic components in the product, and has certain hardness, less proneness to damage and convenience for transportation and carrying.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine health products, in particular to a traditional Chinese medicine tablet with the function of lowering blood fat and a preparation method thereof. Background technique [0002] Hyperlipidemia refers to excessive blood lipid levels, which can directly cause some diseases that seriously endanger human health, such as atherosclerosis, coronary heart disease, pancreatitis, etc. Hyperlipidemia can be divided into two types: primary and secondary. Primary is congenital and hereditary, and is caused by abnormalities in receptors, enzymes, or apolipoproteins involved in lipoprotein transport and metabolism due to single or polygenic defects, or due to environmental factors (diet, nutrition, drugs) ) and by unknown mechanisms. Secondary mostly occurs in metabolic disorders, or is related to other factors such as age, gender, season, drinking, smoking, diet, physical activity, mental stress, emo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/20A61P3/06A61K31/353
CPCA61K9/2054A61K9/2059A61K31/353A61K36/062A61K36/424A61K36/82A61K36/899A61K36/9066A61K2236/19A61P3/06A61K2300/00
Inventor 王洪涛
Owner 郑州桂仁医药科技有限公司
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