SNP genetic marker related to pig feed conversion in FA2H gene fragment

A technology of genetic markers and gene fragments, applied in the field of pig genetics, can solve the problems of high computational intensity, unreasonable setting of significance thresholds, overestimation of marker effects, etc., so as to reduce production costs, reduce feed consumption and breeding. cost, the effect of speeding up the breeding progress

Pending Publication Date: 2019-10-22
FOSHAN UNIVERSITY
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Problems solved by technology

Such methods often face problems such as high computational intensity, overest

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  • SNP genetic marker related to pig feed conversion in FA2H gene fragment
  • SNP genetic marker related to pig feed conversion in FA2H gene fragment
  • SNP genetic marker related to pig feed conversion in FA2H gene fragment

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[0036] The concept, specific structure and technical effects of the present disclosure will be clearly and completely described below in conjunction with the embodiments and drawings, so as to fully understand the purpose, scheme and effect of the present disclosure. It should be noted that, in the case of no conflict, the embodiments in the present application and the features in the embodiments can be combined with each other.

[0037] Such as figure 1 Shown is the working flow chart of the method for screening SNP genetic markers related to pig feed conversion in the FA2H gene fragment according to the present disclosure, combined below figure 1 To illustrate the method for screening SNP genetic markers related to pig feed conversion in the FA2H gene fragment according to the present disclosure.

[0038] The disclosed method for screening SNP genetic markers related to pig feed conversion in FA2H gene fragments specifically includes the following steps:

[0039] (1) Pheno...

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Abstract

The invention discloses an SNP genetic marker related to pig feed conversion in a FA2H gene fragment. Through the identification of a molecular marker ASGA0092975 affecting the weight gain ratio of boar feed, a large effect molecular genetic marker affecting the weight gain ratio of pig feed can be screened; the marker is located at a pig chromosome 6 12904530bp position and belongs to the intronsequence of a FA2H gene, and the position is a C > T mutation, so that the marker is an allele which can reduce the weight gain ratio of the feed; the selection of breeding pigs can be assisted by detecting the genotype of the marker, and a core group can be entered by selecting TT homozygous breeding pigs, so that the weight gain ratio of the feed can be reduced, and feed consumption and breedingcosts can be effectively reduced as well; and in DLY commercial pig groups, the feed weight gain ratio of TT genotype pigs having ASGA0092975 site polymorphism is 0.08 lower than that of CC genotypepigs, and average daily feed intake can be reduced to 187.83 g/day. Thus, the SNP locus can significantly reduce the feed weight gain ratio of domestic pigs; and that T is the allele which can reducethe feed weight gain ratio and the average daily feed intake can be verified.

Description

technical field [0001] The disclosure relates to the technical field of pig genetics, in particular to SNP genetic markers in FA2H gene fragments related to pig feed conversion. Background technique [0002] Feed efficiency, as an important economic trait, has always been the focus of domestic and foreign pig breeding companies and breeding pig improvement companies. In the middle of the 20th century, Feed / Gain ratio (F / G) was used to study feed efficiency at home and abroad, and this trait is a quantitative trait with medium heritability. In 2015, Mignon et al. (Mignon G S, rideau N, Gabriel I, etal. Detection of QTL controlling feed efficiency and excretion in chickens feda wheat-based diet. Genetics Selection Evolution, 47(1):74(2015)) detected in chickens There were 13 QTLs related to feed conversion ratio. According to reports, there are single nucleotide polymorphisms in pigs' Suppressor of Cytokine Signaling 2 (CRADD) gene and Melanocortin 4 receptor (MC4R) gene tha...

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Application Information

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IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/156C12Q2600/124
Inventor 赵云翔邝伟键李智丽喻维维朱晓萍
Owner FOSHAN UNIVERSITY
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