Method for synthesizing N-vinylcarbazole
A technology of vinyl carbazole and carbazole, which is applied in the field of synthesis of N-vinyl carbazole, which can solve the problems of long steps, increased risk factor, and impact on yield, and achieves the effects of mild reaction conditions, low cost, and easy operation
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Embodiment 1
[0016] First add 300ml of ethanol solvent into the 500ml reaction bottle, then add 83g of carbazole, 30g of potassium hydroxide, and 46g of methyl butynol in turn under stirring, gradually raise the temperature to 75°C, and detect the reaction progress by gas phase. When the gas phase peak of the raw material carbazole Completely disappear to stop the reaction, carry out vacuum distillation to remove most of the solvent, then suction filter and wash with water to obtain 88 g of solid crude product (yield 91%).
[0017] The solid crude product was completely dissolved in an appropriate amount of ethanol heated to reflux, and then left to stand at room temperature, white crystals were precipitated, filtered, and dried at room temperature to obtain 78 g of white crystals (yield 81%).
Embodiment 2
[0019] First add 1.2L of ethanol solvent to the 2L reaction flask, then add 334g of carbazole, 120g of potassium hydroxide, and 185g of methyl butynol successively under stirring, and gradually raise the temperature to 80°C. The reaction was stopped when the peak disappeared completely, and most of the solvent was removed by distillation under reduced pressure, then suction filtered and washed with water to obtain 348 g of solid crude product (yield 90%).
[0020] The solid crude product was completely dissolved in an appropriate amount of ethanol that was heated to reflux, and then allowed to stand at room temperature. White crystals were precipitated, filtered, and dried at room temperature to obtain 309 g of white crystals (80% yield).
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