Expired air VOCs detection device for human health continuous self-evaluation and application

Abstract

The invention discloses an expired air VOCs detection device for human health continuous self-evaluation and application. The device comprises a main expired air collection bin, a hydrophobic film fixer, an expiration nozzle, an array sensor, an exhaust fan, an information processing module, a valve, a display screen and other electronic components, wherein the array sensor measures expired air target VOCs signals, the information processing module calculates changes of different target VOCs compared with last measurement results according to measured VOCs levels, and the changes reflect health state changes. Through the expired air VOCs detection device, high-frequency continuous evaluation of comprehensive health conditions can be realized in a large-range crowd, and the device can be used for continuous monitoring and self-evaluation of a sub-health state and a sick degree, drug therapy effect testing, effectiveness evaluation of various intervention factors, etc.

Description

technical field [0001] The invention relates to an exhaled breath VOCs detection device for continuous self-assessment of human health, in particular to a device based on an array sensor that detects common volatile organic compounds (VOCs) related to various diseases in exhaled breath, and then conducts comprehensive evaluation of human health The device and its application belong to the technical field of medical device manufacturing and application. Background technique [0002] The analysis of VOCs components in the exhaled breath of the human body is used to evaluate the health status and disease status of the human body. For example, acetone, dimethyl sulfide, isoprene, butanol, methyl nitrate, and some long-chain alkanes and benzene series were found to have significant abnormal levels in the exhaled breath of diabetic patients; benzene, ethanol, benzene Ethylene, pentane, etc. have been identified as potential markers of lung cancer in many studies; aldehydes and ke...

AI Technical Summary

Problems solved by technology

[0004] However, there are still several problems in the equipment using exhaled VOCs sensor for health assessment: (1) due to the low level of VOCs related to health assessment in exhaled breath (1-100ppb), the accuracy and stability of the sensor itself is not enough for It performs precise quantification and cannot perform health status evaluation based on a few VOCs like large-scale instruments (Jaisutti, R., et al., Acs Applied Materials & Interfaces, 2017.9(10): p.8796-8804.)

Improving the performance of sensors for target exhaled breath VOCs analysis is currently a key research direction, but the progress is still very limited (Righettoni, M., et al., Analytica Chimica Acta, 2012.738: p.69-75.)

(2) There are many types and high concentrations of VOCs in the exhaled breath, and there is serious mutual interference between the responses of different VOCs and a single sensor

(6) The emergence of health problems often does not exist independently

However, the disease diagnosis in this research is based on the relative difference data of VOCs levels in 1404 subjects. The selected VOCs types have not been confirmed in other populations, and the accuracy of product application in other populations cannot be guaranteed; the product does not consider individual differences. The influence of factors on the diagnostic efficiency, and the guarantee of high-frequency calibration is required; the influence of inhaled external air on the relative difference of exhaled VOCs is not considered

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