Wearable animal cardiovascular measuring system

Abstract

The invention relates to a wearable animal cardiovascular measuring system. The wearable animal cardiovascular measuring system comprises an opto-acoustic measuring system for conducting opto-acousticmeasurement on animals and determining animal blood oxygen saturation based on opto-acoustic measuring signals, an electrocardio measuring system for obtaining animal electrocardiogram signals, a signal processing system for comprehensively analyzing blood oxygen saturation signals and the electrocardiogram signals to determine cardiovascular function condition of the animals, and a signal outputsystem for outputting the cardiovascular function condition of the animals. According to the wearable animal cardiovascular measuring system, opto-acoustic measurement and electrocardio measurement can be conducted synchronously when animals are awake and free to move, the convenience and repeatability of operation are improved, the animal infection is reduced, and meanwhile long-term experimental observation can be conducted.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to a wearable animal cardiovascular measurement system. Background technique [0002] Photoacoustic imaging has the advantages of both acoustic imaging and optical imaging, so it has become one of the fastest-growing biomedical imaging technologies in the past decade. Photoacoustic imaging is a novel composite imaging method that obtains the optical absorption characteristics of the sample by detecting the acoustic signal generated by the photoacoustic effect, and constructs a two-dimensional tomographic image or a three-dimensional stereoscopic image of the sample. Photoacoustic imaging can have higher contrast than ultrasound imaging in measuring density and elastic parameters, and can also sensitively reflect the physiological structure of organisms and provide functional information of organisms. Photoacoustic imaging also has the advantages of large imaging depth of acoustic i...

AI Technical Summary

Problems solved by technology

Implantable electrodes will cause trauma to the animal, causing pain and infection in addition to the animal; and when the electrode is clamped to the limbs, the animal's activities will be restricted, and the animal is not like the human body, the human body uses a clip-type During the ECG lead, you can calm down by taking deep breaths, etc., so as to accurately measure the ECG. After the animal is implanted with electrodes or clamped with electrodes, it will appear nervous, manic, etc. due to pain, which will make the measured ECG data inaccurate.

[0005] Some domestic studies have begun to study the photoacoustic imaging system that keeps mice awake and can move freely, such as the animal head-mounted photoacoustic imaging device disclosed in CN104545814A, although it can make mice move in an awake and free state, but The imaging probe is sutured to the animal's head, and the process of suturing the probe is traumatic for the mouse, and it will cause infection, which is extremely inhumane; CN103976709A discloses a wearable array transducer probe, which uses a bowl The transducer is arranged in a bowl-shaped housing, but the bowl-shaped housing can only perform photoacoustic measurements on the head, and cannot perform other measurements on the tail

Moreover, these devices cannot perform ECG measurements, which are limited when it is necessary to understand the animal's cardiac function status

At present, there is no system that allows animals to perform photoacoustic imaging and ECG measurements simultaneously under the condition of keeping animals awake and free to move, and at the same time, the system is not limited by the measurement site

[0006] Furthermore, there is currently no comprehensive system for evaluating cardiovascular function in animals using blood oxygen saturation and ECG signals.

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