Synergistic antioxidant composition of tuna protein hydrolysate and paeoniflorin and application of synergistic antioxidant composition
A technology of protein hydrolyzate and paeoniflorin, which is applied in the direction of drug combination, medical preparations containing active ingredients, anti-toxic agents, etc., can solve the problem of high cost of paeoniflorin, improve antioxidant activity, strong antioxidant capacity, and remove ABTS The effect of free radicals
Active Publication Date: 2020-01-10
BEIJING UNIV OF CHEM TECH +1
View PDF4 Cites 0 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
However, the cost of paeoniflorin is very high. Through testing, we also found that the in vitro antioxidant activity of paeoniflorin needs to be improved. It is necessary to find a low-cost, good biocompatibility, safety, high antioxidant and can synergize with it. Antioxidant Complex
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0028] The configuration is based on mass, tuna protein hydrolyzate:paeoniflorin=1:1 aqueous solution, the total concentration is 3, 1.5, 0.75, 0.38, 0.19, 0.09, 0.05mg / mL. Test its ability to scavenge ABTS free radicals and calculate IC 50 value and CI value.
Embodiment 2
[0030] Configure by mass, tuna protein hydrolyzate:paeoniflorin=2:1 solution, the total concentration is 3, 1.5, 0.75, 0.38, 0.19, 0.09, 0.05mg / mL. Test its ability to scavenge ABTS free radicals and calculate IC 50 value and CI value.
Embodiment 3
[0032] Configure by mass, tuna protein hydrolyzate:paeoniflorin=3:1 solution, the total concentration is 3, 1.5, 0.75, 0.38, 0.19, 0.09, 0.05mg / mL. Test its ability to scavenge ABTS free radicals and calculate IC 50 value and CI value.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
Login to View More Abstract
The invention discloses a synergistic antioxidant composition of a tuna protein hydrolysate and paeoniflorin and an application of the synergistic antioxidant composition, which relate to the technical field of biology. The synergistic antioxidant composition contains tuna protein hydrolysate and paeoniflorin, wherein the mass ratio of tuna protein hydrolysate to paeoniflorin ranges from 1: 7 to 7: 1. The tuna protein hydrolysate and paeoniflorin have the synergistic effect after being mixed in different proportions, so that the antioxidant activity of the tuna protein hydrolysate is effectively improved, and the tuna protein hydrolysate can be used for preparing medicines for preventing and treating diseases related to oxidative stress, such as psoriasis.
Description
technical field [0001] The invention relates to the field of biotechnology, in particular to a synergistic antioxidant composition of tuna protein hydrolyzate and paeoniflorin and application thereof. Background technique [0002] Reactive oxygen species are produced by various enzymatic reactions and chemical processes, which are necessary for many physiological functions in addition to their role as co-messenger in the human body, but when they accumulate excessively in the human body, they may be harmful to neurons function is impaired. Many neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, are characterized by severe or prolonged oxidative stress. The main consequence of oxidative stress is the irreversible damage of macromolecules by reactive oxygen species. Thus, in theory, antioxidant treatment could delay the spread of neuronal damage and improve neurological outcomes. [0003] Paeoniae Alba is a well-known traditional Chinese medic...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/60A61P39/06A61K31/7048
CPCA61K31/7048A61K35/60A61P39/06A61K2300/00
Inventor 黄雅钦杜博玮邓桂雅李雪娟
Owner BEIJING UNIV OF CHEM TECH