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A traditional Chinese medicine composition and its application in treating pullorum of piglets

A technology of piglet pullorum and composition, applied in the field of traditional Chinese medicine compositions, can solve the problems of frequent use of antibiotics and chemical drugs, reduce the effectiveness of drug treatment, improve treatment difficulty and cost, etc., achieve good treatment effect, promote intestinal mucosa recovery, good treatment effect

Active Publication Date: 2021-11-09
ZHEJIANG DKCOM ANIMAL HEALTH PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are still many major problems to be solved urgently in the prevention and treatment of pullorum in piglets: First, there are many serotypes of E. coli that cause pullorum in piglets. So far, there are 171 kinds of E. coli O antigens, 103 kinds of K antigens, and 60 kinds of H antigens.
Second, due to the extensive use of antibiotics and chemical antibacterial drugs, Escherichia coli has produced broad-spectrum drug resistance, which reduces the effectiveness of drug treatment. Clinically, the dose has to be increased and the administration time has to be prolonged, which greatly increases the difficulty and difficulty of treatment. cost
Wang Mingjie et al. monitored the drug resistance of clinically isolated pathogenic bacteria and found that Escherichia coli had a high rate of drug resistance to fluoroquinolone antibacterial drugs, and there was cross-resistance with other antibacterial drugs
Third, the frequent use of antibiotics and chemical drugs has caused serious environmental pollution and endangered public health safety

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Prescription: 850 parts of pomegranate peel, 150 parts of talc

[0056] Preparation method: According to the ratio of parts by weight of the composition, take the pomegranate peel and crush it through a 24-mesh sieve; crush the talc and pass it through a 100-mesh sieve; mix the pomegranate peel powder and the talcum powder evenly, and pack them separately.

[0057] According to the weight of sick piglets, take Pomegranate Peel Zhixie Powder at a dose of 0.09g per 1kg of piglets, and take an appropriate amount of water-soluble powder for continuous use for 5 days. A good effect of 95.0% cure of piglet pullorum was obtained.

Embodiment 2

[0059] Prescription: 850 parts of pomegranate peel, 150 parts of talc

[0060] Preparation method: according to the weight and number ratio of the composition, take pomegranate peel and talc, and make granules according to the above-mentioned granule preparation method.

[0061] According to the weight of sick piglets, take pomegranate peel antidiarrheal granules at a dose of 0.09 g per 1 kg of piglets, and take appropriate amount of water-soluble powder for continuous administration for 5 days. Obtain good effect of 94.6% cure of piglet pullorum.

Embodiment 3

[0063] Prescription: 850 parts of pomegranate peel, 150 parts of talc

[0064] Preparation method: take pomegranate peel and talc according to the ratio of parts by weight of the composition, and prepare the oral liquid according to the above-mentioned oral liquid preparation method.

[0065] According to the body weight of the sick piglets, take pomegranate skin antidiarrheal oral liquid at a dose of 0.09g per 1kg piglets, and take it for 5 consecutive days. Obtain the good effect of 94.8% cure of piglet pullorum.

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Abstract

The invention relates to a traditional Chinese medicine composition and its application in treating white diarrhea of ​​piglets, belonging to the technical field of traditional Chinese medicines for treating diarrhea and diarrhea of ​​piglets. The traditional Chinese medicine composition of the present invention is in the form of traditional Chinese medicine powder, which is administered by oral administration, 0.09 g of piglets per 1 kg of body weight, and used continuously for 5 days. It can effectively treat piglet pullorum with a cure rate of 95.38% and an effective rate of 98.46%, which is comparable to that of the Bailong Powder group of 89.66% and an effective rate of 98.28%. The daily symptom score was significantly lower than that of Bailongsan group (P<0.01); the average course of treatment was only 2.65 days, and the course of treatment was shorter than that of Bailongsan group.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and the application of the composition in treating pullorum of piglets. The invention belongs to the technical field of formulating traditional Chinese medicine and treating animal diseases. Background technique [0002] Piglet pullorum (White Scour of Piglets) is a non-septic, acute intestinal infectious disease of 10-30-day-old piglets caused by pathogenic Escherichia coli. The clinical manifestations are milky white or off-white loose feces, and the feces are pasty, smelly and sticky. Sick pigs are severely dehydrated and the mucous membranes are pale. This disease is popular widely, spreads fast, and the sickness rate can reach 80%, and there is the obvious rising trend. If it is not treated in time or treated properly, it will affect the growth and development of piglets in mild cases, and cause stiff pigs in severe cases, causing huge economic losses to the pig industry. Prim...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61P1/12A61P31/04A61K33/12
CPCA61K33/12A61K36/185A61P1/12A61P31/04A61K2300/00
Inventor 兰新财缪雨臻赵丽丽安丽娜叶志惠麻军法卢骏郑守乾陈欣叶菁欧彬
Owner ZHEJIANG DKCOM ANIMAL HEALTH PROD