Organ fat non-invasive quantitative detection system based on magnetic resonance principle

A detection system and magnetic resonance technology, which is applied in the directions of magnetic resonance measurement, nuclear magnetic resonance spectrum measurement, magnetic variable measurement, etc., can solve the problems of poor reliability of results, large damage, high cost, etc., and achieve high cost performance, convenient operation, Wide range of effects

Inactive Publication Date: 2020-02-11
MARVEL STONE HEALTHCARE CO LTD
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Problems solved by technology

[0004] The purpose of the present invention is to provide a non-invasive quantitative detection system for organ fat based on the principle of magnetic resonance, which reasonably solves the problem of high cost, large damage, and inapplicability of early screening detection and conventional ultrasound in organ fat detection in the prior art. The problem of high subjectivity of imaging detection, poor reliability of results, and inability to realize quantitative detection

Method used

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  • Organ fat non-invasive quantitative detection system based on magnetic resonance principle
  • Organ fat non-invasive quantitative detection system based on magnetic resonance principle
  • Organ fat non-invasive quantitative detection system based on magnetic resonance principle

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Embodiment

[0023] Such as Figure 1-4 A non-invasive quantitative detection system for organ fat based on the principle of magnetic resonance is shown, including a portable magnet module, a radio frequency RF subsystem, a data processing and display module, and is characterized in that:

[0024] The portable magnet module is provided with a portable magnet, and the arrangement of the portable magnet includes at least a small unilateral magnet, and the portable magnet is arranged as an ergonomic curved surface that is attached to the body surface adjacent to the target sample organ, and the back is connected A yoke is provided, the back of the yoke is connected with a handle, and the portable magnet module generates a static magnetic field B 0 , is used to polarize hydrogen atoms in the region of interest (ROI) of the target sample, the static magnetic field B 0 Determined the precession frequency of hydrogen atoms under NMR conditions and the frequency B corresponding to the radio frequ...

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Abstract

The invention discloses an organ fat non-invasive quantitative detection system based on a magnetic resonance principle. The organ fat non-invasive quantitative detection system is characterized in that a radio frequency (RF) subsystem, a portable magnet module and a data processing and display module are adopted to jointly construct a low-field nuclear magnetic resonance system. When the low-field nuclear magnetic resonance system acts on a human body, organs, tissues and cells are not damaged and wounded. Accurate, non-invasive and safe organ fat quantitative detection is achieved, and the organ fat non-invasive quantitative detection system has the advantages of being light, easy to carry, high in cost performance, accurate in quantification and the like. The organ fat non-invasive quantitative detection system is convenient to operate, is not limited by the qualification of operators, achieves one-key detection within a few minutes, is used for rapidly and economically screening related diseases such as NAFLD, metabolic syndrome, non-alcoholic steatohepatitis (NASH) and the like, and has a wide application range. The defects in the prior art are overcome.

Description

technical field [0001] The invention relates to the technical field of nuclear magnetic resonance medical detection, in particular to a non-invasive quantitative detection system for organ fat based on the principle of magnetic resonance. Background technique [0002] About 25% of the global population is suspected to have non-alcoholic fatty liver disease (NAFLD), and many remain undiagnosed due to the lack of feasible, realistic and accurate methods for early detection and monitoring. The current gold standard for diagnosing NAFLD is liver biopsy, which is expensive and invasive, and is not suitable for early detection. Conventional ultrasound imaging is widely used, but it can only provide qualitative information and is highly operator-dependent. In addition, cases of obesity and excess subcutaneous fat are common in NAFLD patients, and ultrasonography is difficult to obtain reliable results. Conventional MRI is an emerging NAFLD status monitoring technique, which has b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01R33/46G01R33/36A61B5/055
CPCA61B5/055G01R33/3607G01R33/4616
Inventor 吴子岳克里希纳·纳亚克王超陈潇
Owner MARVEL STONE HEALTHCARE CO LTD
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