Anti-aging facial mask

[0032] Example 1

[0033] An anti-aging mask containing the following components: butylene glycol 2%, glycerol 5%, 1,2-pentanediol 2%, placental active substance 3%, lycopene fermented extract 8%, grape seed essential oil 2 %, ascorbyl tetraisopalmitate 0.08%, hydrolyzed hyaluronic acid 0.03%, acetylated sodium hyaluronate 0.02%, polyquaternium 0.04%, dipotassium glycyrrhizinate 0.05%, tocopherol acetate 0.04%, hydrogenated Lecithin 0.03%, sorbitol 0.05%, carbomer 0.8%, the rest is sterile distilled water.

[0034] Among them, the tomato pulp was beaten and crushed by a juice machine, sealed for 8 days at a temperature of 30°C, and then sealed and fermented at 20°C for 15 days to obtain a fermentation broth. The fermentation broth is filtered to remove residues such as skin, seeds and fibers, and alkali is added to adjust the pH value of 7.5, heated and stirred at 50°C for 5 hours, and the pH value is adjusted to 4.0. Carotenoid aggregation precipitation is allowed to stand, and the upper turbid liquid is removed to obtain lycopene fermentation extract precipitation.

[0035] Add 0.2% pectinase and cellulase mixture to the lycopene precipitation, in which the mass ratio of pectinase and cellulase is 1:1, treat at 50℃ for 3h to remove 90% of pectin and fiber Centrifuge for 10 min at 10000r/min for non-pigmented substances such as lycopene, wash the precipitate with 96% ethanol, filter, and extract again with ethanol and vegetable oil to separate the oil phase product to obtain the lycopene fermentation extract.

[0036] At the same time, the placenta used in the placental active substance is the healthy placenta of full-term goats, and the placental amniotic membrane and chorionic membrane are used as the placenta. The weight ratio of amniotic membrane to chorionic membrane is 1:5.

[0037] The method for extracting placental active substances is as follows: under aseptic conditions, the goat placental tissue is cut into tissue pieces <0.5mm with a tissue scissors, and the amniotic membrane and chorionic membrane are crushed by ultrasound with a weight ratio of 1:5. -5min, add trypsin collagenase I 0.1% and collagenase II 0.1%, continue shaking and hydrolyzing at 37℃ for 2 hours, centrifuge at 4℃ 10000rpm for 15min, after precipitation, obtain crude placenta extract, the crude extract is Sephadex G-100 gel chromatography column separation, BSA (66kDa), carbonic anhydrase (29kDa) and aprotinin (6.5kDa) as molecular weight markers, dextran blue (200kDa) as the column pore volume marker, the eluent is pH7. 6, 0.2M NaH 2 PO 4 --NaHPO 4 Buffer, the elution rate is controlled at 0.5ml/min, the protein efflux is monitored by a spectrophotometer, the efflux fractions are collected at 10-66Kda, distilled water is dialyzed to remove salt, and the placental active substance is obtained.

[0038] Among them, glycerin, butylene glycol, carbomer, hydrolyzed hyaluronic acid, dipotassium glycyrrhizinate, acetylated sodium hyaluronate, sorbitol and sterile distilled water are mixed into a stirring pot and heated to 80°C, stirred and dissolved completely to prepare Obtain phase A; at the same time add ascorbyl tetraisopalmitate, tocopherol acetate, hydrogenated lecithin, and heat to 80℃ in a stirring pot to obtain phase B; finally add phase B to phase A, emulsify and homogenize for 10 minutes, Cool down to 37°C, add polyquaternary ammonium salt and stir evenly, then add placental active material, lycopene fermented extract, grape seed essential oil and 1,2-pentanediol, mix well and discharge the material to obtain the present invention In the anti-aging mask.

[0039] Example 2

[0040] An anti-aging mask containing the following components: butylene glycol 4%, glycerol 1%, 1,2-pentanediol 1%, placental active substance 5%, lycopene fermented extract 10%, grape seed essential oil 1 %, ascorbyl tetraisopalmitate 0.1%, hydrolyzed hyaluronic acid 0.05%, acetylated sodium hyaluronate 0.01%, polyquaternium 0.05%, dipotassium glycyrrhizinate 0.01%, tocopherol acetate 0.05%, hydrogenated Lecithin 0.01%, sorbitol 0.04%, carbomer 1%, the rest is sterile distilled water.

[0041] Among them, glycerin, butanediol, carbomer, hydrolyzed hyaluronic acid, dipotassium glycyrrhizinate, acetylated sodium hyaluronate, sorbitol and sterile distilled water are mixed into a stirring pot and heated to 85°C, stirred and dissolved completely to prepare Obtain phase A; at the same time, add ascorbyl tetraisopalmitate, tocopherol acetate, hydrogenated lecithin, and heat to 85°C in a stirring pot to obtain phase B; finally add phase B to phase A, emulsify and homogenize for 10 minutes, Cool down to 35°C, add polyquaternary ammonium salt and stir evenly, then add placental active material, lycopene fermentation extract, grape seed essential oil and 1,2-pentanediol, fully stir evenly and discharge the material to obtain the present invention In the anti-aging mask.

[0042] Other technical features are the same as in Embodiment 1, and will not be repeated here.

[0043] Example 3

[0044] An anti-aging facial mask containing the following components: butylene glycol 1%, glycerin 8%, 1,2-pentanediol 4%, placental active substance 2%, lycopene fermented extract 6%, grape seed essential oil 4 %, ascorbyl tetraisopalmitate 0.05%, hydrolyzed hyaluronic acid 0.01%, acetylated sodium hyaluronate 0.05%, polyquaternium 0.02%, dipotassium glycyrrhizinate 0.1%, tocopherol acetate 0.02%, hydrogenated Lecithin 0.06%, sorbitol 0.08%, carbomer 0.5%, the rest is sterile distilled water.

[0045] Among them, glycerin, butylene glycol, carbomer, hydrolyzed hyaluronic acid, dipotassium glycyrrhizinate, acetylated sodium hyaluronate, sorbitol and sterile distilled water are mixed into a stirring pot and heated to 70°C, stirred and dissolved completely to prepare Obtain phase A; at the same time add ascorbyl tetraisopalmitate, tocopherol acetate, hydrogenated lecithin, add them to a stirring pot and heat to 70°C to obtain phase B; finally add phase B to phase A, emulsify and homogenize for 10 minutes, Cool down to 40°C, add polyquaternium salt and stir evenly, then add placental active material, lycopene fermented extract, grape seed essential oil and 1,2-pentanediol, fully stir evenly and discharge the material to obtain the present invention In the anti-aging mask.

[0046] Other technical features are the same as in Embodiment 1, and will not be repeated here.