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Application of aqueous extract of cordyceps militaris sporophore in liver protection product

A technology of water extract and grass seeds, applied in the application field of fruit body water extract in liver protection products, can solve the problems of lack of comparative systematic evaluation reports on the antioxidant activity of Cordyceps militaris mycelium, and achieve the prevention and treatment of fatty liver. Effect

Inactive Publication Date: 2020-03-27
FUJIAN AGRI & FORESTRY UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is a lack of systematic evaluation reports on the antioxidant activity of Cordyceps militaris mycelia, fermentation broth, and fruiting bodies

Method used

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  • Application of aqueous extract of cordyceps militaris sporophore in liver protection product
  • Application of aqueous extract of cordyceps militaris sporophore in liver protection product
  • Application of aqueous extract of cordyceps militaris sporophore in liver protection product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0046] The water extract of the fruit body of Cordyceps militaris is used in liver protection medicine to make capsules. The water extract of fruiting body of Cordyceps militaris accounts for 70% of the total mass of the hepatoprotective drug, and other components are auxiliary drugs and materials.

Embodiment 3

[0048] The water extract of the fruit body of Cordyceps militaris is used in liver protection medicine to make pills. The water extract of fruiting body of Cordyceps militaris accounts for 20% of the total mass of the hepatoprotective drug, and other components are auxiliary drugs and materials.

[0049] Hepatoprotective Drug Example 4

[0050] The water extract of fruit body of Cordyceps militaris is used in liver protection medicine to make granules. The water extract of fruiting body of Cordyceps militaris accounts for 65% of the total mass of the hepatoprotective drug, and other components are auxiliary drugs and materials.

[0051] Hepatoprotective Drug Example 5

[0052] The water extract of the fruit body of Cordyceps militaris is used in liver protection medicine to make microcapsules. The water extract of fruiting body of Cordyceps militaris accounts for 100% of the total mass of the hepatoprotective drug, and other components are auxiliary drugs and materials.

...

Embodiment 7

[0056] The water extract of fruit body of Cordyceps militaris is used in liver protection medicine to make syrup. The water extract of fruiting body of Cordyceps militaris accounts for 25% of the total mass of the hepatoprotective drug, and other components are auxiliary drugs and materials.

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Abstract

The invention discloses an application of an aqueous extract extracted from cordyceps militaris sporophore in liver protection products, and belongs to the technical field of medicines and foods. Highantioxidant active sites of cordyceps militaris MF27 are screened, the aqueous extract extracted from sporophore of the cordyceps militaris MF27 is found to have the best scavenging effect on DPPH free radicals and hydroxyl free radicals with EC50 values of 0.167 mg / mL and 0.245 mg / mL, respectively. The aqueous extract with high antioxidant activity is applied to liver protection products (such as liver protection medicines and liver protection health care products) with a percentage accounting for 0.5-100% of the liver protection products, and the liver protection products are found to playa good role in preventing and relieving liver diseases such as fatty liver, alcoholic liver, viral hepatitis and drug-induced hepatitis. The application provides a theoretical basis for development and application of liver protection products related to cordyceps militaris.

Description

technical field [0001] The invention belongs to the technical field of medicine and food, and in particular relates to the application of the fruiting body water extract of Cordyceps militaris in liver protection products. Background technique [0002] Cordyceps militaris Cordyceps militaris (L.)Fr., also known as Cordyceps militaris, belongs to the Ascomycota, Hypotheca, Ergotaceae, and Cordyceps, and is one of the three traditional Chinese tonics. It is rich in active ingredients such as Cordyceps polysaccharide, cordycepin, cordycepic acid and Cordyceps SOD, and has good anti-oxidation, anti-tumor, anti-virus and liver protection effects. In recent years, the antioxidant activity of Cordyceps militaris has become a focus of attention, mainly focusing on the research of its single component or extract. At present, there is a lack of systematic evaluation reports on the antioxidant activity of Cordyceps militaris mycelia, fermentation broth, and fruiting bodies. [0003]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/068A61P1/16A21D2/36
CPCA21D2/36A61K36/068A61P1/16
Inventor 傅俊生吴小平戚梦袁源
Owner FUJIAN AGRI & FORESTRY UNIV
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