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Preparation method of high-hygroscopicity alginate dressing

A technology with high hygroscopicity and alginate, which is applied in the field of medical supplies, can solve problems such as the instability of nano-silver and the high toxicity of human cells, and achieve the effect of promoting wound healing, accelerating the recovery of skin tissue, and improving the antibacterial effect

Inactive Publication Date: 2020-03-31
山东星之诚生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Adding antibacterial agents to calcium alginate dressings will improve the antibacterial properties of the dressing and improve its functions; nano-silver has strong anti-bacterial properties, but due to the instability of nano-silver and its high toxicity to human cells

Method used

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  • Preparation method of high-hygroscopicity alginate dressing
  • Preparation method of high-hygroscopicity alginate dressing
  • Preparation method of high-hygroscopicity alginate dressing

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Embodiment 1

[0024] Such as Figure 1 to Figure 3 The highly hygroscopic alginate dressing of the present invention comprises a dressing body soaked in a soaking solution; the dressing body is made of multilayer alginate fiber monomers through weaving and compounding; the soaking solution includes the following components by weight: Raw materials: 2~5 parts of tea polyphenols, 1~8 parts of aloe extract, 0.005~0.01 parts of recombinant human epidermal growth factor, 1~5 parts of betaine, 100.6~7 parts of polyglycerol and 1~5 parts of carbomer .

[0025] The alginate fiber monomer is calcium alginate fiber prepared by wet spinning from a spinning solution of sodium alginate.

[0026] The calcium alginate fiber is in the form of helical rotating fiber, wave extension or helical cross structure.

[0027] The alginate fiber monomers in the upper and lower adjacent layers are arranged horizontally and vertically.

Embodiment 2

[0029] The structure of the highly hygroscopic alginate dressing of the present invention is the same as that of Example 1, wherein the alginate fiber monomer is calcium alginate fiber prepared by 3D printing from a spinning solution of sodium alginate.

Embodiment 3

[0031] The preparation method of highly hygroscopic alginate dressing of the present invention comprises the following steps:

[0032] The first step is to prepare the soaking solution. According to the ratio, take 3 parts of tea polyphenols, 6 parts of aloe extract, 0.006 parts of recombinant human epidermal growth factor, 3 parts of betaine, 104 parts of polyglycerol and 2 parts of carbomer to add to the formula Stir in deionized water with a total weight ratio of 1:57 at a temperature of 25°C to obtain a uniformly mixed soaking solution;

[0033] The second step is soaking. Soak the dressing body composed of 8 layers of alginate fiber monomers made by wet spinning in the soaking solution, the soaking temperature is 28°C, and the soaking time is 7 hours;

[0034] The third step is to freeze and sterilize, take out the soaked alginate fiber dressing, and place it in a freeze-drying box to freeze-dry; sterilize with ethylene oxide to obtain a suction-type highly hygroscopic al...

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Abstract

The invention discloses a preparation method of a high-hygroscopicity alginate dressing. The high-hygroscopicity alginate dressing comprises a dressing body soaked with a soaking solution, wherein thedressing body is formed by weaving and compounding a plurality of layers of alginate fiber monomers; wherein the soaking solution is prepared from the following raw materials in parts by weight: 2 to5 parts of tea polyphenol, 1 to 8 parts of an aloe extract, 0.005 to 0.01 part of recombinant human epidermal growth factor, 1 to 5 parts of betaine, 0.6 to 7 parts of polyglycerol-10 and 1 to 5 parts of carbomer; the preparation method comprises the following steps: step 1, preparing a soaking solution; step 2, soaking; and 3, freezing and sterilizing; the alginate dressing has high absorbability, and can form gel on a wound surface to keep the wound moist; natural antibacterial components are added, so that the effects of antisepsis and anti-inflammation are achieved, safety and non-toxicity are achieved, and wound recovery is facilitated.

Description

technical field [0001] The invention relates to a method for preparing a highly hygroscopic alginate dressing, which belongs to the technical field of medical supplies. Background technique [0002] When treating a patient's wound, it is necessary to cover the wound with a dressing to prevent bacterial invasion and water loss; although traditional dressings such as gauze and cotton pads can protect the wound surface, they have poor moisturizing and fluid absorption capabilities and can only absorb their own weight. 4~5 times, and for some wounds, when the traditional dressing is removed, the dressing is easy to adhere to the wound tissue, causing secondary wound damage. [0003] The medical dressing made of calcium alginate fiber can ion-exchange with wound exudate and sodium ions in the blood to release calcium ions, which can accelerate the formation of blood clots at the end of capillaries and have a good hemostatic effect; During use, calcium alginate is gradually conve...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/40A61L15/20A61L15/44A61L15/46
CPCA61L15/28A61L15/40A61L15/20A61L15/44A61L15/46A61L2300/30A61L2300/404A61L2300/412A61L2300/414C08L5/04
Inventor 邵星之
Owner 山东星之诚生物科技有限公司
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