Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for constructing GC-MC fingerprint of ferula asafetida volatile oil and application of ferula asafetida volatile oil

A technology of volatile oils and medicines, which is applied in the construction of GC-MC fingerprints of Ferulicum volatile oil and its application field, which can solve the problems of less research on the chemical components and pharmacological effects of Ferulicum ferulae

Active Publication Date: 2020-05-05
新疆医科大学第四附属医院
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, after reviewing the literature, it is found that there are few studies on the chemical constituents and pharmacological effects of Junggar Ferulicum

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for constructing GC-MC fingerprint of ferula asafetida volatile oil and application of ferula asafetida volatile oil
  • Method for constructing GC-MC fingerprint of ferula asafetida volatile oil and application of ferula asafetida volatile oil
  • Method for constructing GC-MC fingerprint of ferula asafetida volatile oil and application of ferula asafetida volatile oil

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] 1. Experimental materials

[0035] 1.1 Cell lines: human gastric cancer SGC-7901, human umbilical vein endothelial cells (HUVECs), purchased from the Institute of Cells, Chinese Academy of Sciences, Shanghai, cells of passage 3-5 were used in the experiments.

[0036] 1.2 Medicinal materials: identified as Ferulasinkiangensis, Ferula ferulaeoides, and Ferula songoriea by the chief Chinese pharmacist of the Affiliated Hospital of Xinjiang Medical University.

[0037] 1.3 Reagents: Endothelial cell ECM-2 medium (Scien Cell, USA); fetal bovine serum (FBS) (Hyclone, USA, batch number F160123); phosphate buffered saline (PBS) (Hyclone, USA, batch number AC10257442); RPMI- 1640 medium (U.S. Gibco Company, batch number AD16192263); dimethyl sulfoxide (DMSO) (U.S. Sigma Company, batch No. 67685TT); penicillin / streptomycin solution (U.S. Hyclone Company, batch No. J170016); MTT (U.S. Sigma Company, batch No. J170016); Batch No. EZ2811D347); with Matrigel Transwell chamber (Amer...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
ionization potentialaaaaaaaaaa
Login to View More

Abstract

The invention provides application of ferula asafetida volatile oil in preparation of drugs for resisting tumor angiogenesis, tumor cell proliferation or tumor cell invasion and migration. The invention also provides a construction method of a GC-MC fingerprint of the ferula asafetida volatile oil. Results of experimental research prove that the ferula asafetida volatile oil can effectively inhibit angiogenesis and inhibit the tubulation capacity of endothelial cells; the ferula asafetida volatile oil can inhibit the proliferation, migration and invasion of tumor cells and has good anti-tumorcell metastasis capacity; and the effect of the ferula soongorica volatile oil is optimal in experiments of a variety of ferula asafetida volatile oil.

Description

technical field [0001] The invention relates to a method for constructing GC-MC fingerprints of Ferula volatile oil and its application, especially the application in the preparation of drugs for anti-tumor angiogenesis, anti-tumor cell proliferation or anti-tumor cell invasion and migration. Background technique [0002] Junggar ferula (Ferula songoriea Pall) is a plant of the genus Ferula in the family Umbelliferae, and its medicinal parts are root and oil gum resin. In Kazakhstan and other folks, it is used to treat headaches, colds, stomach problems and other diseases, and it is widely distributed in Altay, Tacheng and other places in Xinjiang. [0003] The medicinal ferulae included in the "Chinese Pharmacopoeia" (2015 edition) is the resin of Ferulasinkiangensis K.M.Shen or Ferula fukanensis K.M.Shen of Umbelliferae. It tastes bitter, pungent, warm, and Spleen and Stomach Meridian. It has the effects of digesting food, transforming disease, dispelling lumps and killi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/23A61P35/00A61P35/04G01N30/02G01N30/72
CPCA61K36/23A61P35/00A61P35/04G01N30/02G01N30/72
Inventor 赵生俊张海英卢军张柏生范芳芳陈良轩辕欢张彦
Owner 新疆医科大学第四附属医院
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com