Traditional Chinese medicine preparation for treating thromboangiitis obliterans through oral administration and external application, preparation method for traditional Chinese medicine preparation and application of traditional Chinese medicine preparation

A traditional Chinese medicine preparation and a technology of thrombosis occlusion, applied to the field of traditional Chinese medicine preparation and its preparation for oral administration and external application for the treatment of thromboangiitis obliterans, can solve the problems of large oral dosage and single use method, and achieve good stability and effective drug effect Guaranteed, easy-to-use effect

Inactive Publication Date: 2020-06-02
GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Patent CN103830426 B, a traditional Chinese medicine composition for treating vasculitis, proposes a Chinese medicine compound and its preparation method, which can better treat vasculitis. However, in the course of further research and use, it is found that its oral Large dose, single method of use

Method used

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  • Traditional Chinese medicine preparation for treating thromboangiitis obliterans through oral administration and external application, preparation method for traditional Chinese medicine preparation and application of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for treating thromboangiitis obliterans through oral administration and external application, preparation method for traditional Chinese medicine preparation and application of traditional Chinese medicine preparation

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Embodiment

[0031] The components were weighed according to the following formula: Niu Dali 24g, Rehmannia glutinosa 12g, Angelica 18g, Achyranthes bidentata 24g, Caulis Spatholobus 12g, Hedyotis diffusa 6g, Jinniu 6g, and Two heads 6g.

[0032] Prepare Chinese medicine preparation according to the following steps:

[0033] Preparation of S1 Achyranthes bidentata concentrate:

[0034] Take Achyranthes bidentata and add 3 times the volume of medicinal materials at 50°C, 70% ethanol for dynamic extraction at low temperature for 3 times, each time for 12 hours; filter, recover ethanol from the filtrate, form a concentrated solution of Achyranthes bidentata, and save it for later use;

[0035] Preparation of S2 topical liquid medicine:

[0036] Take Niu Dali and Angelica sinensis, add 4 times the volume of medicinal materials in water and soak for 0.5 hours, then distill with steam distillation for 1.5 hours to extract the volatile oil, add the obtained volatile oil to the Achyranthes bident...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating thromboangiitis obliterans through oral administration and external application. The traditional Chinese medicine preparation comprises ingredients such as radix millettiae speciosae, prepared rehmannia roots, radix angelicae sinensis, radix achyranthis bidentatae, spatholobus stems, herba hedyotidis diffusae, zanthoxylum nitidum and rhizoma anemones raddeanae. A preparation method comprises the following steps: S1. preparation of a radix achyranthis bidentatae concentrate; S2. preparation of an external-application liquid medicine; S3. preparation of clear paste A; S4. preparation of clear paste B; and S5. preparation of oral-administration granules. Compared with common oral-administration traditional Chinesemedicine mixtures in clinical application, the traditional Chinese medicine preparation provided by the invention and a use method have the advantages that the preparation process and the use methodare combined with the traditional traditional Chinese medicine theories and clinical application requirements and have a targeted medication advantage, the drug effect is better guaranteed, and the use is more convenient.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine preparation for oral administration and external application for treating thromboangiitis obliterans and its preparation method and application. Background technique [0002] Thromboangiitis obliterans (vasculitis) is one of the common types of peripheral arterial occlusive disease. It is an aseptic vascular inflammatory disease that occurs in the small and medium arteries and veins of the extremities, mainly involving small and medium blood vessels and nerves in the distal extremities. Especially in the blood vessels of the lower extremities, the vascular wall will produce periodic and non-suppurative inflammation, often accompanied by intraluminal thrombus, which can cause pain, ischemia, intermittent walking and other symptoms in the limbs, and in severe cases, it can cause limb ulcers or necrosis. Most patients are forced...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/08A61K9/16A61P9/14
CPCA61K9/0014A61K9/0095A61K36/21A61K36/232A61K36/486A61K36/71A61K36/748A61K36/758A61K36/804A61P9/14A61K2300/00
Inventor 郭洁文黎建华钟世顺
Owner GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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