Novel 2019-nCoV coronavirus rapid detection immunochromatographic test strip

Abstract

The invention discloses a novel 2019-nCoV coronavirus rapid detection immunochromatographic test strip. A sample pad, a combination pad, a nitrocellulose membrane and a water absorption pad are sequentially bonded on a bottom plate in a mutual lap joint manner; a 2019-nCoV recombinant structural protein-fluorescent marker and a goat anti-chicken IgY antibody-fluorescent marker are sprayed on the combination pad; the nitrocellulose membrane is provided with a first detection line coated with an anti-human mu chain antibody, a second detection line coated with an anti-human IgG antibody, and a control line coated with chicken IgY, and the detection lines and the control line are spaced from each other. The novel 2019-nCoV coronavirus detection immunochromatographic test strip can be used forrapidly detecting a specific antibody IgM or IgG of a patient,has the advantages of being rapid, accurate and high in positive detection rate, is suitable for being used for rapid detection and timely restraining propagation and spreading of 2019-nCoV novel coronas at present, and enables patients to be treated according to symptoms.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to an immunochromatographic test strip for rapid detection of 2019-nCoV novel coronavirus. Background technique [0002] At present, there is no specific treatment for Corona Virus Disease 2019 (COVID-19), but many symptoms can be treated and should be treated according to the clinical condition of the patient. Each case of COVID-19 must collect acute phase respiratory specimens (throat swab, nasal swab, nasopharyngeal aspirate, deep cough sputum, respiratory aspirate, bronchial lavage fluid, alveolar lavage fluid, lung biopsy specimens) etc.) and blood samples. Respiratory samples are mainly used for nucleic acid detection and antigen detection, and serum samples are mainly used for COVID-19 virus-specific antibody IgM or IgG detection. Among them, the specific antibody IgM is the earliest antibody in the initial humoral immune response, appearing in about a week. The detection of...

AI Technical Summary

Problems solved by technology

The 2019-nCoV new coronavirus nucleic acid detection kit was first successfully developed and put into use, but its detection takes at least 40 minutes, and the throughput of nucleic acid detection equipment is relatively small, which is far from meeting the detection needs of a large number of suspected cases in hospital outpatient clinics

In addition, nucleic acid detection has high professional requirements for laboratory equipment and operators, which cannot be realized in primary hospitals.

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