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Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood, and preparation method of Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood

A technology of composition and capsule, which is applied in the field of Yougui Busui Shengxue Capsule traditional Chinese medicine composition and its preparation, and can solve problems such as side effects and unsatisfactory curative effect of aplastic anemia

Inactive Publication Date: 2020-07-03
陕西郝其军制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inventor has done a lot of research on the prior art, and found that the 5 types disclosed in the above patent bulletin have unsatisfactory curative effects in the treatment of aplastic anemia, and have some side effects.

Method used

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  • Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood, and preparation method of Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood
  • Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood, and preparation method of Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood
  • Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood, and preparation method of Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0092] The present invention is made from the raw material medicine of following weight ratio:

[0093]

[0094] Its preparation method is as follows:

[0095](1) Preparation of Zihe powder: Take the fresh human placenta tissue that has been tested by immunology, boil it in 4% pepper water until it floats on the water surface, remove it, remove surface impurities, put it in the oven, dry it below 70°C for 12 hours, take it out , let cool, pass through an 80-mesh sieve, and obtain;

[0096] (2) Preparation of bovine bone marrow powder: take fresh bovine bone marrow, add water to decoct three times, add 6 times the amount of water for the first time, decoct for 2 hours, add 4 times the amount of water for the second and third times, decoct for 1.5 hours respectively, and combine Decoction, filtration, and when the filtrate is concentrated to 80°C, the clear paste with a relative density of 1.10-1.12 is measured, dried below 80°C, pulverized, and passed through a 80-mesh siev...

Embodiment 2

[0099] The present invention is made from the raw material medicine of following weight ratio:

[0100]

[0101]

[0102] Its preparation method is as follows:

[0103] (1) Preparation of Zihe powder: Take the fresh human placenta tissue that has been tested by immunology, boil it in 4% pepper water until it floats on the water surface, remove it, remove surface impurities, put it in the oven, dry it below 70°C for 12 hours, take it out , let cool, pass through an 80-mesh sieve, and obtain;

[0104] (2) Preparation of bovine bone marrow powder: take fresh bovine bone marrow, add water to decoct three times, add 6 times the amount of water for the first time, decoct for 2 hours, add 4 times the amount of water for the second and third times, decoct for 1.5 hours respectively, and combine Decoction, filtration, and when the filtrate is concentrated to 80°C, the clear paste with a relative density of 1.10-1.12 is measured, dried below 80°C, pulverized, and passed through a...

Embodiment 3

[0107] The present invention is made from the raw material medicine of following weight ratio:

[0108]

[0109] Its preparation method is as follows:

[0110] (1) Preparation of Zihe powder: Take the fresh human placenta tissue that has been tested by immunology, boil it in 4% pepper water until it floats on the water surface, remove it, remove surface impurities, put it in the oven, dry it below 70°C for 12 hours, take it out , let cool, pass through an 80-mesh sieve, and obtain;

[0111] (2) Preparation of bovine bone marrow powder: take fresh bovine bone marrow, add water to decoct three times, add 6 times the amount of water for the first time, decoct for 2 hours, add 4 times the amount of water for the second and third times, decoct for 1.5 hours respectively, and combine Decoction, filtration, and when the filtrate is concentrated to 80°C, the clear paste with a relative density of 1.10-1.12 is measured, dried below 80°C, pulverized, and passed through a 80-mesh sie...

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Abstract

The invention discloses a Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood, and a preparation method of the Yougui capsule traditional Chinese medicine composition for reinforcing bone marrow and generating blood. The traditional Chinese medicine composition is prepared through steps of processing 12 raw medicines in a certain compounding ratio of processed prepared aconite roots, cinnamon, fried bead deerhorn glue, prepared rehmannia roots, Asiatic cornelian cherry fruits stir-fried with wine, Chinese yams, Chinese wolfberry fruits, semen cuscutae, cortex eucommiae stir-fried with salt, radix angelica sinensis, ox bone marrow powder, and placenta hominis powder to obtain medicine active components, and through granulation, drying, and loading in capsules, Yougui capsules for reinforcing bone marrow and generating blood are prepared, wherein the placenta hominis powder is selected from fresh human placenta tissue subjected to immunodetection, decoction is performed with pepper water of 4%, impurities are removed, drying under 70 DEG C or below is performed, screening is performed through an 80-mesh sieve, to obtain the placenta hominis powder, and in the obtained placenta hominis powder, active components of placenta hominis are reserved to the maximum extent; and the ox bone powder is selected from fresh ox bone marrow, decoction is performed with water, concentration is performed to obtain sugarless cream, drying at 80 DEG C or below is performed, crushing is performed, and screening is performed through an 80-mesh sieve, so that the ox bone powder is prepared, and active components of the ox bone marrow are reserved to the maximum extent for the obtained ox bone marrow powder. The composition has the efficacy ofwarming and recuperating kidney yang, reinforcing marrow and generating blood, is suitable for patients suffering from aplastic anemia of deficiency of kidney yang, leukopenia and the like, with manifestations of pale complexion, light lip and nail color, palpitation, short of breath, spontaneous perspiration and fatigue, vertigo and blurred vision, anorexia, loose stool, cold limbs, swollen limbs, cold body and mild facial edema. Compared with the prior art, the Yougui capsule traditional Chinese medicine composition is significant in treatment effects on aplastic anemia of deficiency of kidney yang, higher in bioavailability and free from toxic and side effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition of Yougui Busui Shengxue capsule and a preparation method thereof, belonging to the technical field of pharmacy. Background technique [0002] Aplastic anemia is mainly a syndrome in which the number of hematopoietic stem cells is reduced or the function is abnormal due to various reasons, thereby causing PB red blood cells, white blood cells and thrombocytopenia. It is difficult to treat clinically and seriously affects people's health. Traditional Chinese medicine has a lot of Chinese medicine compositions in the treatment of aplastic anemia. Because there are many causes of aplastic anemia, it is difficult in the treatment process, and most of the curative effects are not very satisfactory at present. Traditional Chinese medicine has fewer Chinese patent medicines for the treatment of kidney-yang deficiency aplastic anemia and leukopenia, which cannot meet the existing clinical need...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P7/00A61P7/06A61K9/48A61K35/32A61K35/50
CPCA61K9/16A61K35/32A61K35/50A61K36/232A61K36/39A61K36/40A61K36/43A61K36/46A61K36/54A61K36/714A61K36/804A61K36/815A61K36/8945A61K2236/331A61K2236/39A61K2236/51A61P7/00A61P7/06A61K2300/00
Inventor 郝彬董昌虎
Owner 陕西郝其军制药股份有限公司
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