Gel dressing for preventing and treating human papillomavirus infection and preparation method thereof

Abstract

The invention discloses a gel dressing for preventing and treating human papillomavirus infection. The gel dressing is prepared by taking a CP protein, carbomer, carboxylated chitosan, glycerol and Arabic gum as main raw materials, wherein the mass percentages of the raw materials are as follows: 0.01-0.1% of the CP protein, 0.1-1% of the carbomer, 0.1-1% of the carboxylated chitosan, 5-15% of theglycerol, 0.5-3% of the Arabic gum and the balance of water. According to the invention, the CP protein is used as a main effective component, and the whole CP protein is negatively charged, can be combined with HPV viruses to inactivate the HPV viruses, and has repair capability on damaged tissues. The invention also discloses an application of the gel dressing in preparing medicaments for preventing and treating human papillomavirus infection.

Description

technical field

[0001] The invention belongs to the field of medicine and hygiene, and in particular relates to a gel dressing for preventing and treating human papillomavirus (HPV) infection and a preparation method. Background technique

[0002] In the 1980s, German virologist Harald Zur Hausen first proposed that HPV infection is closely related to cervical cancer. In 1995, the special meeting of IRAC (International Organization for Research on Cancer) confirmed that HPV infection is a necessary condition for cervical cancer. 99.7% HPV can be detected in cervical cancer tissue, and cervical cancer will hardly occur in those who are not infected with HPV (negative predictive value >99%). Due to the discovery of the cause of cervical cancer, Hausen became one of the winners of the 2008 Nobel Prize in Medicine.

[0003] High-risk HPV is a protein-coated virus with the smallest double-stranded DNA. There are currently more than 100 types of HPV. It is a mucous membrane an...

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