Traditional Chinese medicine monomer for treating early endometriosis and application thereof
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology for endometriosis and ectopic diseases, applied to medical preparations containing active ingredients, drug combinations, pharmaceutical formulas, etc.
Pending Publication Date: 2020-09-22
YUEYANG INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL SHANGHAI UNIV OF CHINESE TRADITIONAL MEDICINE
View PDF3 Cites 0 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
Other studies on the drug's treatment of endometriosis have not been reported
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0052] Embodiment 1 Chinese medicine granules
[0053] The preparation method is as follows:
[0054] Take traditional Chinese medicine monomer ginsenoside Rg3 and granule auxiliary agent, and prepare according to the conventional preparation method of granule.
Embodiment 2
[0055] Embodiment 2 Chinese medicine capsule
[0056] The preparation method is as follows:
[0057] Take traditional Chinese medicine monomer ginsenoside Rg3 and capsule auxiliary agent, and prepare according to the conventional preparation method of capsule.
Embodiment 3
[0058] The therapeutic effect of embodiment 3 ginsenoside Rg3 on endometriosis rats
[0064] (1) Ginsenoside Rg3 was purchased from Shanghai Shengzhong Pharmaceutical Chemical Co., Ltd.; batch number 140321; content ≥ 95%; white powder.
[0065] (2) Gestrinone was purchased from Beijing Zizhu Pharmaceutical Co., Ltd.; batch number 06001011002; content 99.9%; white powder.
[0066] 1.2 Experimental method
[0067] 1.2.1 Feeding and estrous cycle monitoring of female SD rats:
[0068] Adult female SD rats were kept in the SPF-level rodent experimental animal room of Shanghai Institute of Family Planning Scien...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention relates to a traditional Chinese medicine monomer for treating early endometriosis and application thereof. The traditional Chinese medicine monomer is ginsenoside Rg3. Results show thatthe ginsenoside Rg3 can inhibit angiogenesis of ectopic endometrium of an endometriosis rat, but does not affect the form of the endometrium in situ, which indicates that physiological blood vesselsare not affected by the ginsenoside Rg3, so that the ginsenoside Rg3 has extremely low toxicity to normal tissues. Therefore, the ginsenoside Rg3 can be applied to early treatment of endometriosis andtreatment of residual lesions in laparoscopic surgery to prevent relapse without hindering ovulation, and conforms to ideal drugs for early treatment and prevention of endometriosis. In addition, ginsenoside Rg3 can obviously lower the level of serum E2 of rats suffering from endometriosis, but has no obvious influence on the serum P level, so that the ginsenoside Rg3 is prompted to adjust the in-vivo endocrine environment by adjusting the in-vivo hormone level, does not affect pregnancy while treatment diseases, is the most effective treatment for EMs, and is high in practicability.
Description
technical field [0001] The invention relates to the technical field of application of traditional Chinese medicine monomers, in particular to a traditional Chinese medicine monomer for treating early endometriosis and its application. Background technique [0002] Endometriosis (endometriosis, EMs) is a common and intractable disease in gynecology. It is characterized by persistent pelvic pain and infertility caused by the growth of endometrium outside the uterine cavity. lesion. The most typical symptom of this disease is secondary and progressive pain in the lower abdomen and lumbosacral region, which usually occurs 1 to 2 days before menstruation, and is the worst on the first day after menstruation. Disappears during menstruation. The etiology and pathogenesis of endometriosis are complex and changeable, and complications such as pain, infertility, and ovarian cancer risk seriously affect women's quality of life. The clinical etiology and pathogenesis of endometriosis...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more