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Preparation method for eucommia ulmoides extract containing genipin and chlorogenic acid active ingredients

A technology of active ingredients and extracts, which is applied in the field of Eucommia extract preparation, can solve problems such as waste of resources, and achieve the effect of low cost and simple and easy method

Inactive Publication Date: 2020-10-02
GUIZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Eucommia ulmoides is used as a traditional Chinese medicine for skin, and the leaves are discarded, resulting in waste of resources

Method used

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  • Preparation method for eucommia ulmoides extract containing genipin and chlorogenic acid active ingredients
  • Preparation method for eucommia ulmoides extract containing genipin and chlorogenic acid active ingredients
  • Preparation method for eucommia ulmoides extract containing genipin and chlorogenic acid active ingredients

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Embodiment

[0022] A preparation method of Eucommia ulmoides extract containing active components of genipin and chlorogenic acid.

[0023] 1) Treatment of eucommia leaves: eucommia leaves are picked in spring, dried at 80-90°C, pulverized by a pulverizer and passed through an 80-mesh sieve to obtain ultrafine powder of eucommia leaves;

[0024] 2) Extraction: Add 32 times the volume of distilled water to the superfine powder of Eucommia leaves obtained in 1), soak at room temperature for 2 hours, and stir several times during the process;

[0025] 3) Water bath extraction: Put the solution obtained in 2) in a water bath pot for water bath extraction for 2 hours, the water bath extraction temperature is 80-90°C, and stir several times during the extraction process;

[0026] 4) Centrifuge and repeat extraction: Centrifuge the extract obtained in 3) at room temperature and 10,000 rpm for 5 minutes, repeat the extraction of the filter residue 5 times, and combine the filtrate 1-5 times;

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Abstract

The invention discloses a preparation method for a eucommia ulmoides extract containing genipin and chlorogenic acid active ingredients. The preparation method is characterized by comprising the following steps: 1) drying fresh eucommia ulmoides leaves, and carrying out crushing and sieving so as to prepare eucommia ulmoides leaf superfine powder; 2) weighing the eucommia ulmoides leaf superfine powder, adding distilled water, carrying out soaking, then carrying out extraction in a water bath, centrifuging an extract, collecting a supernatant, and repeatedly extracting filter residue for a plurality of times; 3) weighing the supernatant, and carrying out drying so as to obtain the eucommia ulmoides extract; and 4) weighing a proper amount of the eucommia ulmoides extract, and determining the active ingredients of the eucommia ulmoides extract through a gas chromatography-mass spectrometry technology.

Description

technical field [0001] The invention belongs to the field of extracts of traditional Chinese medicinal materials, and in particular relates to a method for preparing an extract of Eucommia ulmoides containing active ingredients of genipin and chlorogenic acid. Background technique [0002] Eucommia ( Eucommia ulmoedes oliver), also known as Sizhong, silk cotton tree and jade silk bark, is a rare and precious medicinal tree species unique to my country. Eucommia bark and Eucommia leaves contain lignans and glycosides, iridoids (including genipale), phenylpropanoids (including chlorogenic acid, etc.), flavonoids, polysaccharides, Eucommia gum, biological It also contains vitamins, trace elements, amino acids, polysaccharides and other nutritional ingredients, which have multiple functions such as anti-inflammatory, antibacterial, anti-oxidation, lowering blood sugar, enhancing immune function, and anti-fatigue. Eucommia ulmoides is used as a traditional Chinese medicine for...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/46A61P39/06A61P29/00A61P31/04A61P37/02
CPCA61K36/46A61K2236/15A61K2236/17A61K2236/331A61K2236/39A61K2236/51A61P29/00A61P31/04A61P37/02A61P39/06
Inventor 赵德刚雷跃宋莉李民学赵懿琛
Owner GUIZHOU UNIV