A kind of anti-hair loss liquid and preparation method thereof
An anti-hair loss and hair growth and water solution technology, which is applied in the field of daily chemicals, can solve the problems of hair loss period, male side effects, and rapid hair loss, etc., and achieve a good sense of use and the effect of promoting hair growth
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Embodiment 1
[0024] The selection of embodiment 1 solvent kind
[0025] Weigh 50 g of ethanol, 30 g of 1,3 propylene glycol, 18 g of water, and 2 g of pyrrolidinyl diaminopyrimidine respectively, mix and stir until completely dissolved, and obtain hair tonic I.
[0026] Weigh 50 g of ethanol, 30 g of glycerol, 18 g of water, and 2 g of pyrrolidinyl diaminopyrimidine respectively, mix and stir until completely dissolved, and obtain hair tonic II.
[0027] Weigh 50 g of ethanol, 30 g of 1,3-butanediol, 18 g of water, and 2 g of pyrrolidinyl diaminopyrimidine respectively, mix and stir until completely dissolved, and obtain hair tonic III.
Embodiment 2
[0028] Embodiment 2 stability test
[0029] Put the hair tonic I-III prepared in Example 1 in a stability test box at a temperature of 40°C, and take them out for 0, 1, 2, 3, and 6 months respectively, and observe the color, smell, and solubility. The results are as follows: As shown in Table 1, the color of Hair Tonic III has not changed for 6 months, and the stability is good, so 1,3-butanediol should be preferred as the solvent.
[0030] Table 1 Stability test results
[0031]
Embodiment 3
[0032] Embodiment 3 skin irritation test
[0033] Hair growth liquid I-III is carried out skin irritation test, rabbit is divided into 4 groups, every group of 4, i.e. blank group (water is test object), experimental group 1 (hair growth liquid I is test object), experimental group 2 ( Hair tonic II is the test object) Experimental group 3 (hair tonic III is the test object), the rabbits in each group are selected to shave the back fur with an area of 4cm*4cm, and then apply hair tonic I, II, III, once a day in the morning and evening, 0.5ml each time, observe the situation of each group of rabbits.
[0034] The results showed that: after 5 days and 7 days of hair tonic I and II respectively, dermatitis and redness appeared in different degrees in the experimental area. Dermatitis, redness and swelling occurred in Hair Tonic III, and the test was continued. At 4 weeks, 1 rabbit had slight inflammation and redness, which indicated that the solvent of Hair Tonic III was the l...
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