Method for manufacturing artificial vitreous device suitable for children with oculo-cerebro-renal syndromes
A technology for renal syndrome and vitreous body, applied in the direction of eye implants, etc., can solve problems such as the inability to adapt to the adjustment of intraocular pressure, and the difficulty in adapting the shape and volume to the patient's developmental requirements.
Active Publication Date: 2020-10-16
BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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[0013] The invention provides a method for making an artificial vitreous body device suitable for children with ocular-cerebral-renal syndrome, so as to solve the problem that the shape and volume of the existing artificial vitreous body cannot adapt to the developmental requirements of the patient after implantation, and the intraocular pressure cannot be adjusted question
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[0068] In order to have a clearer understanding of the technical features, purposes and effects of the present invention, the present invention will now be described with reference to the accompanying drawings.
[0069] like figure 2 , Figure 7a , Figure 7b , Figure 7c As shown, the present invention proposes an artificial vitreous device suitable for children with oculocerebral-renal syndrome, which includes:
[0070] Silicone rubber membrane 1, also known as microelastic membrane, is in the shape of a film. The thickness of a simple film is 20 μm, which exceeds the thickness of a conventional artificial vitreous body (10 μm). The period of use shall not be less than 5 years. The silicone rubber membrane 1 has a port filled with silicone oil and an internal closed space connected to the port. The silicone rubber membrane is film-like when unfolded into a plane, and becomes a three-dimensional spherical or apple-like shape after being filled with silicone oil;
[0071...
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The invention provides a method for manufacturing an artificial vitreous device suitable for children with oculo-cerebro-renal syndromes. The method comprises the following steps of: A, manufacturinga silicon rubber membrane; B, pouring a wire mesh on the inner wall of the silicon rubber membrane; C, installing a valve at the port of the silicon rubber membrane; and D, installing an auxiliary pipe in the valve, and sealing the auxiliary pipe by using an elastic sealing surface. The artificial vitreous device for children with oculo-cerebro-renal syndromes manufactured by the invention can beadaptive to change of the 1.5-2.0 cm eyeball diameter of children; the intraocular pressure tolerance is + / -2 KPa; and, due to the self-sealing valve, the abrasion phenomenon of the valve in the priorart is avoided.
Description
technical field [0001] The invention relates to the field of ophthalmic medical devices, in particular to a method for making an artificial vitreous device suitable for children with ocular-cerebral-renal syndrome. Background technique [0002] Oculo-cerebral-renal syndrome, also known as Lowe syndrome, is a rare sex-linked recessive genetic disease. Clinically, it is characterized by congenital cataracts, mental retardation, and renal tubular acidosis. Defects exist at birth, but symptoms mostly appear in infancy or later. Eye, brain, and kidney lesions can also appear at different ages. [0003] The ocular symptoms of Lowe syndrome include: congenital bilateral cataract, accompanied by congenital glaucoma; vitreous opacity, severe visual impairment, only light perception or total blindness; coarse nystagmus and photophobia are often present. [0004] Lowe syndrome can be divided into infancy, childhood and adulthood according to the natural history. In infancy, it is ch...
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IPC IPC(8): A61F2/14
CPCA61F2/14
Inventor 樊云葳李宁东李莉刘雯梁天蔚吴倩曹文红王媛
Owner BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV