Magnesium alloy degradable stent applied to curved pathological cerebral vascular

Abstract

The present invention provides a magnesium alloy degradable stent applied to curved pathological cerebral vascular. The magnesium alloy degradable stent includes a plurality of main structure supporting rings, the main structure supporting rings are connected and surround in turn to form a tubular structure, every two adjacent main structure supporting rings are connected by connecting ribs, and each main structure supporting ring is composed of a plurality of sine wave-shaped main units. The stent is made of magnesium alloy degradable materials, can be degraded in a human body, adopts a relative low metal coverage integrally, is high in flexibility under the condition of ensuring sufficient supporting force, and is suitable for the features of tortuous and brittle intracranial blood vessels, and asymmetric design enable the stent to be more suitable for the curved pathological blood vessels.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a magnesium alloy degradable stent applied to curved and diseased cerebral blood vessels. Background technique [0002] Intracranial atherosclerosis is the most common vascular lesion in patients with cerebrovascular disease and one of the most common causes of stroke worldwide. With the progress of aging in my country and the unhealthy lifestyle of some people, the incidence of cerebrovascular disease has increased to 8.7%. The speed is increasing year by year. There are about 2 million new cases of cerebrovascular disease in my country every year, and about 1.5 million patients die of cerebrovascular disease every year. The international authoritative medical journal "The Lancet" published a blockbuster paper in June this year, which analyzed the causes of death of residents in 34 provinces in China (including Hong Kong, Macao and Taiwan) from 1990 to 2017. ...

AI Technical Summary

Problems solved by technology

2. Most of the stent designs only consider linear blood vessels

When the bending arc increases, the upper unit of the stent will warp and protrude into the vessel wall, and in severe cases, the vessel wall will be scraped

While the units on the lower side of the bend overlap and collide, studies have found that multiple adjacent or overlapping stents will cause adverse blood turbulence, which may lead to the formation of thrombus and eventually lead to restenosis

For drug-loaded stents, this curvature can also cause uneven drug release

Therefore, it is obviously impossible to meet the requirements only by considering the straight-line stent structure design, and it is very necessary to design a stent structure specifically for curved lesioned cerebral vessels.

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