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Traditional Chinese medicine composition for treating psoriasis

A composition and psoriasis technology, applied in drug combination, skin disease, pharmaceutical formula, etc., can solve problems such as low recurrence rate and unsatisfactory control of recurrence rate

Active Publication Date: 2020-11-06
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The invention patent application with the publication number CN 105213971A discloses a "Chinese medicine composition for treating psoriasis", which is made of 5 Chinese herbal medicines: Sargassum, Curcuma, Ume, Smilax and Radix Paeoniae Rubra, but the present invention Further studies have found that the traditional Chinese medicine composition is still not ideal in controlling the recurrence rate, so it is of great significance to develop a drug for the treatment of psoriasis with a low recurrence rate

Method used

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  • Traditional Chinese medicine composition for treating psoriasis
  • Traditional Chinese medicine composition for treating psoriasis
  • Traditional Chinese medicine composition for treating psoriasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0120] Embodiment 1 (granule)

[0121] 1. Prescription:

[0122] Raw astragalus 300g, Rehmannia glutinosa 150g, bran-fried Atractylodes macrocephala 150g, Smilax tuckahoe 300g, red peony 150g, vinegar curcuma 100g, vinegar turtle 300g, ebony plum 150g, sarcophagus 150g.

[0123] 2. Preparation method:

[0124] (1) Take the vinegar turtle, add water and decoct for 30 minutes, then add the remaining raw materials, and decoct 3 times; each time add 10 times the amount of water according to the weight of all raw materials, and continue for 45 minutes after boiling;

[0125] (2) Combine 3 decoctions, filter, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30 at 25°C, and dry it at 65°C to form a dry paste;

[0126] (3) Take the dry paste prepared in step (2) and grind it into fine powder, add appropriate amount of dextrin and starch, mix well, add water to make granules, then dry, granulate, and pack into 10g / bag.

Embodiment 2

[0127] Embodiment 2 (ointment)

[0128] 1. Prescription:

[0129] Raw astragalus 300g, rehmannia glutinosa 150g, bran fried Atractylodes macrocephala 150g, Smilax tuckahoe 300g, red peony root 150g, vinegar curcuma 100g, vinegar vinegar turtle 300g, ebony 150g, sarcophagus 150g.

[0130] 2. Preparation method:

[0131] (1) Take the turtle shell in vinegar and vinegar, add water and decoct for 30 minutes, then add the remaining raw materials and decoct 3 times; each time add 10 times the amount of water according to the weight of all raw materials, and continue for 45 minutes after boiling;

[0132] (2) Combine 3 decoctions, filter, and concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30 at 25°C, and set aside;

[0133] (3) Get honey and boil under 110 ℃ of normal pressure conditions to the honey liquid that relative density is 1.3 under 100 ℃;

[0134] (3) Take the thick paste prepared in step (2) and heat and stir it evenly at 1...

Embodiment 3

[0135] Embodiment 3 (capsules)

[0136] 1. Prescription:

[0137] Raw astragalus 360g, Rehmannia glutinosa 156g, bran-fried Atractylodes macrocephala 156g, Smilax tuckahoe 262g, red peony 122g, vinegar curcuma 86g, vinegar turtle 296g, black plum 156g, sarcophagus 156g.

[0138] 2. Preparation method:

[0139] (1) Take the vinegar turtle, add water and decoct for 30 minutes, then add the remaining raw materials, and decoct 3 times; each time add 8 times the amount of water according to the weight of all raw materials, and continue for 30 minutes after boiling;

[0140] (2) Merge three decoctions, filter, concentrate the filtrate under reduced pressure to a thick paste with a relative density of 1.30 at 25°C, and dry it at 60°C to form a dry paste;

[0141] (3) Take the dry paste prepared in step (2) and grind it into fine powder, add appropriate amount of dextrin and starch, mix well, add water to make granules, then dry, granulate, put into gelatin capsules, and make capsul...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating psoriasis. The traditional Chinese medicine composition is composed of an active ingredient and pharmaceutically acceptable auxiliary materials, and is characterized in that the active ingredient is prepared from the following raw materials in percentage by weight: 14-21% of raw radix astragali, 7-10% of prepared rehmannia rhizomes, 7-10% of bran-fried rhizoma atractylodis macrocephalae, 14-21% of glabrous greenbrier rhizomes, 7-10% of red peony roots, 5-7% of vinegar-processed rhizoma curcumae, 14-21% of vinegar-processed turtle shell, 7-10% of dark plum fruits and 7-10% of glabrous sarcandra herb. The traditional Chinese medicine composition has a remarkable effect on treating the psoriasis.

Description

technical field [0001] The present invention relates to medical preparations, in particular to medicines containing undetermined structures from traditional Chinese medicines, which are suitable for treating psoriasis (psoriasis). Background technique [0002] Psoriasis (PS), commonly known as psoriasis, is a systemic, chronic skin disease with a genetic predisposition. At present, there are 10 million PS patients in my country, and the prevalence rate is increasing year by year. There are about 125 million PS patients in the world, accounting for about 2-3% of the total population. Psoriasis has many complications, including psoriatic arthritis, cardiovascular and cerebrovascular diseases, psychiatric complications, chronic kidney disease, inflammatory bowel disease, liver disease, certain malignancies and infections, and has a significant impact on the patient's quality of life. big negative impact. [0003] At present, there is no cure for psoriasis, and most of the tre...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P17/06A61K35/586
CPCA61K36/481A61K36/804A61K36/284A61K36/90A61K36/896A61K36/71A61K36/65A61K36/9066A61K35/586A61K36/736A61K36/185A61P17/06A61K2236/331A61K2236/39A61K2300/00
Inventor 卢传坚陈海明邓浩赵瑞芝韩凌叶舒妍陈更新
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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