Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of medicinal preparation in preparation of medicine for treating senile dementia

A pharmaceutical preparation, a technology for senile dementia, applied in the field of new clinical uses of drugs

Inactive Publication Date: 2020-11-13
QIONGLAI TIANYIN PHARM CO LTD
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no low-toxic and effective specific drug in clinical practice

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of medicinal preparation in preparation of medicine for treating senile dementia
  • Application of medicinal preparation in preparation of medicine for treating senile dementia
  • Application of medicinal preparation in preparation of medicine for treating senile dementia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Embodiment 1 pharmaceutical preparation oral liquid solution preparation

[0044] (1), extraction:

[0045] Put honey ring powder 100Kg into the frying bag, the filling amount is 1 / 5~1 / 2 of the frying bag, put it in a multifunctional extraction tank and add water.

[0046] (2), concentration:

[0047] Combine the extracts, filter, concentrate the filtrate to a relative density of 1.14-1.15, and collect the paste.

[0048] (3), alcohol precipitation:

[0049] Pump the cooled extract into an alcohol precipitation tank, accurately add ethanol, and stir while adding, so that the alcohol content of the medicinal solution reaches 75%, refrigerate, and stand still.

[0050] (4), ethanol recovery:

[0051] Extract the supernatant after alcohol precipitation and concentrate in a vacuum concentrator, recover ethanol at the same time, and concentrate to a relative density of 1.15-1.17.

[0052] (5), dosing:

[0053] a. Preparation of Ginkgo biloba extract solution

[0054] ...

Embodiment 2

[0059] The preparation of embodiment 2 capsules

[0060] 1), extraction:

[0061] Put honey ring powder 110Kg into the decoction bag, place in the extraction tank and add water to extract 3 times, and collect the extract;

[0062] (2), concentration:

[0063] Combine step (1) extracts, filter, concentrate the filtrate to a relative density of 1.10-1.16, and collect the paste;

[0064] (3), alcohol precipitation:

[0065] Pump the extract from the above step (2) into an alcohol precipitation tank, add ethanol and stir, so that the alcohol content of the medicinal solution reaches 60% to 80%, refrigerate, and stand;

[0066] (4), ethanol recovery:

[0067] Extract the supernatant after alcohol precipitation to concentrate in a vacuum concentrator, recover ethanol at the same time, and concentrate to honey ring powder extract with a relative density of 1.15-1.17;

[0068] (5), mixing

[0069] Get 4Kg of ginkgo leaf extract again, after mixing evenly, add appropriate amount ...

Embodiment 3

[0070] The preparation of embodiment 3 dropping pills

[0071] (1), extraction:

[0072] Put honey ring powder 120Kg into a frying bag, put it in an extraction tank and add water to extract 1-3 times, and collect the extract;

[0073] (2), concentration:

[0074] Combine step (1) extracts, filter, concentrate the filtrate to a relative density of 1.10-1.16, and collect the paste;

[0075] (3), alcohol precipitation:

[0076] Pump the extract from the above step (2) into an alcohol precipitation tank, add ethanol and stir, so that the alcohol content of the medicinal solution reaches 60% to 80%, refrigerate, and stand;

[0077] (4), ethanol recovery:

[0078] Extract the supernatant after alcohol precipitation to concentrate in a vacuum concentrator, recover ethanol at the same time, and concentrate to honey ring powder extract with a relative density of 1.15-1.17;

[0079] (5), drop system

[0080] Take the extract prepared in the honey ring powder (4) and 2Kg of ginkgo ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to application of a medicinal preparation in preparation of a medicine for treating senile dementia. The pharmaceutical preparation is prepared from the following raw material medicines, by weight: 2-4 parts of ginkgo leaf extract and 80-120 parts of armillaria mellea L. The invention aims to provide a novel clinical treatment application of the pharmaceutical preparation intreating senile dementia to widen the clinical application adaptation disease range of the pharmaceutical preparation and provide a novel medication choice for senile dementia patients.

Description

technical field [0001] The application of a pharmaceutical preparation of the invention in the preparation of medicines for treating senile dementia belongs to the field of new clinical applications of medicines. Background technique [0002] Senile dementia can be divided into Alzheimer's (AD) dementia, vascular dementia and the coexistence of the two types. However, clinically, AD is more common, and most of them are caused by organic brain damage, which leads to the degradation of memory, understanding, judgment and control, and intellectual impairment, which seriously affects the daily life of patients. The prevalence of senile dementia in my country is about 2% to 5%, but with age, there is a gradual upward trend. At present, there are about 1% new cases each year, and the mortality rate of senile dementia ranks fourth in the mortality rate of common diseases, second only to cardiovascular and cerebrovascular diseases, tumors and strokes. With the further development ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/16A61P25/28
CPCA61K36/07A61K36/16A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P25/28A61K2300/00
Inventor 赵涛刘建勋徐立王益民张颖任建勋张建卢露
Owner QIONGLAI TIANYIN PHARM CO LTD