Aromatic acid compound and application

A compound and acid technology, applied in the field of medicine, can solve the problem of no methyl mandelate
CN102584915AInactive Publication Date: 2012-07-18SHENYANG PHARMA UNIVERSITY

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
SHENYANG PHARMA UNIVERSITY
Publication Date
2012-07-18
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention belongs to the field of medicine, and relates to an aromatic acid compound separated from dry mature seeds of Prunuspersica (L.) Batsch or Prunusdavidiana (Carr.) Franch. and application of the aromatic acid compound in medicaments for preventing and treating senile dementia. The compound has the following structure, and is prepared by the steps of extraction, concentration, extraction, concentration and purification; and the compound has an obvious protective effect on damage of Abeta (25-35)-induced neuroblastoma cell strains SH-SY5Y, and has an effect of preventing and treating the senile dementia.
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Description

technical field

[0001] The invention relates to an aromatic acid monomer compound and its application, belonging to the technical field of medicine. Background technique

[0002] Alzheimer's disease (Alzheimer's disease, AD) was first discovered by the neuropathologist Alzheimer in 1906 and named after him. AD is a diffuse central neurodegenerative disease, a common senile neurodegenerative disease characterized by progressive cognitive impairment, mental decline, and personality changes, accounting for about 50% to 60% of all dementias. According to reports, about 3% of the elderly aged 65-74 suffer from AD, and the prevalence rate of the population aged 75-84 is 19%, while the prevalence of AD among the elderly aged > 85 is higher than 47%. The fourth leading cause of death in the elderly. Although there is a lack of authoritative and representative statistics for developing countries, it is estimated that 60% of the world's dementia patients exist in developing coun...

Claims

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