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A micro-target screening device based on multi-needle array vibration excitation fluid

A technology of vibration excitation and screening device, which is applied in the direction of enzymology/microbiology device, biochemical cleaning device, bioreactor/fermenter for specific purposes, etc. Experimental operation cost, the effect of realizing automation

Active Publication Date: 2022-02-15
BEIJING INSTITUTE OF TECHNOLOGYGY
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Problems solved by technology

[0005] In order to solve the problem that the current technology cannot quickly and non-destructively screen micro-targets, the present invention provides a micro-target screening device based on multi-needle array vibration excitation fluid, which can meet the safety and efficiency requirements of cell screening at the same time

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  • A micro-target screening device based on multi-needle array vibration excitation fluid
  • A micro-target screening device based on multi-needle array vibration excitation fluid
  • A micro-target screening device based on multi-needle array vibration excitation fluid

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Embodiment Construction

[0044] In order to enable those skilled in the art to better understand the solutions of the present application, the technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application.

[0045] see figure 1 , which is a schematic structural diagram of a micro-target screening device based on multi-needle array vibration excitation fluid provided by an embodiment of the present invention.

[0046] A micro-target screening device based on multi-needle array vibration excitation fluid, characterized in that it includes a three-degree-of-freedom operating platform 1, a manual displacement stage 2, a metal array plate 3, an electron microscope 7, a glass slide 8, a processing unit and three More than one vibration unit, wherein the vibration unit includes a metal connector 4 , a vibration generator 5 and a glass needle 6 .

[0047] The metal array plate 3 i...

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Abstract

The invention provides a micro-target screening device based on multi-needle array vibration excitation fluid, through the joint vibration of multiple vibration generators, a specific flow field is formed in a liquid environment, and different micro-targets are driven to pass through the flow field along different paths, thereby realizing Screening of micro-targets; it can be seen that the present invention can not only achieve non-damaging screening of cells, but also significantly improve the efficiency of micro-target screening, and is easy to automate, reducing the cost of micro-target screening; compared with existing micro-targets The screening method, the present invention can significantly improve the experimental efficiency and reduce the cost of experimental operation in the field of life science research related to micro-target screening, has a wide range of application prospects, and is expected to have good economic benefits in the field of life science research and industry.

Description

technical field [0001] The invention belongs to the technical field of micro-nano operation, and in particular relates to a micro-target screening device based on multi-needle array vibration excitation fluid. Background technique [0002] With the rapid development of micro-nano technology, the current society pays more and more attention to micro-operation. Whether it is in vitro fertilization in clinical medicine, cloning technology in biological research, or three-dimensional observation of cells in medical research, it is necessary to screen out the cells that best meet the current experimental conditions based on the physical characteristics of individual cells. [0003] The current screening operations for tiny spherical objects are mainly divided into contact operations and non-contact operations. The contact manipulator is the main method of contact operation. Since the micro-manipulation of the contact manipulator directly operates on the biological target, it has...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/34C12M1/00
CPCC12M47/04C12M41/46C12M41/48
Inventor 刘晓明李磊李玉洋黄强新井健生
Owner BEIJING INSTITUTE OF TECHNOLOGYGY
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