Therapy method based on photodynamic therapy system, and photodynamic therapy system

Abstract

The invention discloses a therapy method based on a photodynamic therapy system, and the photodynamic therapy system. The method comprises the following steps of: obtaining a fluorescence image generated when a photosensitizer on a tissue to be treated is irradiated; calculating the fluorescence image according to a fluorescence image processing algorithm, and determining the overexposure area andthe underexposed area of the fluorescence image; analyzing the overexposure area and the underexposed area of the fluorescence image according to a pre-set convolutional neural network model, and determining excitation light doses required by various points of the fluorescence image; and performing therapy by generating the therapy light intensity according to the excitation light doses requiredby various points of the fluorescence image. By implementation of the therapy method based on the photodynamic therapy system, and the photodynamic therapy system in the invention, the fluorescence image, the overexposure area and the underexposed area of which are marked, can be input into the pre-set convolutional neural network model; the excitation light parameters required by various points of the best fluorescence image can be determined and obtained according to output of the pre-set convolutional neural network model; therefore, optimal imaging is obtained by the minimum exposure time;and fluorescent bleach due to the excessive exposure time of the photosensitizer is reduced.

Description

technical field [0001] The invention relates to the technical field of photodynamic diagnosis and treatment equipment, in particular to a treatment method based on a photodynamic therapy system and a photodynamic therapy system. Background technique [0002] Photodynamic therapy requires the use of light to excite the photosensitizer, and the photosensitization effect produced by the photosensitizer is used to kill the diseased tissue. Because the light itself is controllable in the intensity, time and area of ​​irradiation, and the photosensitizer has little effect on non-irradiated areas, photodynamic therapy is an ideal precision treatment method. At the same time, photosensitizers can be used for fluorescence imaging, so it is a very promising technology for clinical application to use photosensitizer distribution and other information obtained by photosensitizer fluorescence imaging to guide photodynamic irradiation and realize precise photodynamic therapy. [0003] At...

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Problems solved by technology

[0004] In view of this, the embodiment of the present invention provides a treatment method based on a photodynamic therapy system and a photodynamic therapy system to solve the problem of using multiple exposure...

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