Ultrasonic device for combined imaging and cyclic focusing transmission transdermal drug delivery and control method

Abstract

The invention discloses an ultrasonic device for combined imaging and cyclic focusing transmission transdermal drug delivery. The ultrasonic device comprises an ultrasonic host and an ultrasonic transducer array integrated with imaging and treatment functions, wherein the ultrasonic transducer array is used for converting an electric signal into an acoustic signal, converting the acoustic signal into an electric signal, transmitting different ultrasonic fields and generating different receiving effects according to different signal waveforms, amplitudes and phases; and the ultrasonic host is used for driving the ultrasonic transducer array to complete transmission and receiving required by imaging and complete transmission required by transdermal drug delivery, so that ultrasonic cyclic focusing transmission is realized, and an ultrasonic focusing channel from shallow to deep is formed. According to the control method, cyclic focusing transmission is adopted, and a continuous relatively strong sound field in the vertical depth direction can be formed on a transdermal drug delivery channel, so that continuous driving force is provided for drug particles, the drug particles can reacha relatively deep subcutaneous lesion, and drug permeation is better performed.

Description

technical field [0001] The invention relates to an ultrasonic device combined with imaging and cyclic focusing emission for transdermal drug delivery and a control method, belonging to the technical field of medical devices. Background technique [0002] Ultrasound is a mechanical vibration with a vibration frequency exceeding 20,000 Hz, which is generally generated by an ultrasonic transducer and can propagate in solids, liquids, and gases. Ultrasound with a certain power can be used in medical treatment, transdermal drug delivery, physical therapy and beauty treatment, etc. In order to achieve more convenient control and more powerful functions, several ultrasonic transducers are generally combined into an array, and different ultrasonic waves are emitted under the control of the control circuit to meet different business needs. [0003] Ultrasonic imaging is to transmit ultrasonic waves into the human body and reflect them after encountering objects. According to the amp...

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Problems solved by technology

[0006] These devices can carry out targeted drug delivery and improve the efficiency of ultrasonic transdermal drug delivery to a certain extent, but there are still some shortcomings: 1. The transdermal drug delivery device is not closely integrated with the guidance of the imaging device, or the imaging device needs to be replaced after positioning. Transdermal drug delivery reduces the guidance accuracy, making it impossible to carry out precise targeted transdermal drug delivery; 2. The focal area in the ultrasonic field is where the intensity of the sound wave is the largest and the particle vibration direction is vertical to the depth direction. The penetration effect is strongest deep in the human body, and these devices only have one focus position, which cannot effectively push the drug particles for a long distance in the depth direction

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