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Anti-hair loss plant extract, preparation method thereof and application of plant extract

A plant extract and an extraction method technology are applied in the field of anti-hair loss plant extract and its preparation, which can solve the problems of adverse reactions of the cardiovascular system, infant birth defects, and difficult to cure both the symptoms and the root causes, and achieve the goal of promoting blood circulation in the head and inhibiting the scalp. The effect of oil secretion and enhancement of autophagy activity

Pending Publication Date: 2020-12-04
SHANGHAI JAKA BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the anti-hair loss products on the market have a single mechanism of action, and it is difficult to treat both symptoms and root causes
[0003] The best anti-hair loss drugs are western medicine minoxidil and finasteride, but long-term use will have obvious side effects. Among them, finasteride can cause allergic reactions such as itching, urticaria, and facial swelling. Women’s use can cause baby’s eczema. Birth defects and sexual dysfunction, minoxidil is likely to cause severe hirsutism on the face and limbs for women, dryness, desquamation, itching, redness and other irritating reactions are likely to occur on the part of the drug, and it may also cause certain cardiovascular diseases. Systemic adverse reactions
Plant-derived anti-hair loss ingredients are safe and non-toxic, but due to unreasonable formulations or inappropriate preparation processes, the efficacy is generally not ideal, and plant extracts also have stability problems

Method used

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  • Anti-hair loss plant extract, preparation method thereof and application of plant extract
  • Anti-hair loss plant extract, preparation method thereof and application of plant extract
  • Anti-hair loss plant extract, preparation method thereof and application of plant extract

Examples

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preparation example Construction

[0043] A second aspect of the present invention provides a method for preparing the anti-hair loss plant extract as described above, comprising the following steps:

[0044] a. Extract ginger or dried ginger;

[0045] b. mixing and extracting the remaining raw materials except ginger or dried ginger;

[0046] c. merging the products obtained in step a and step b to get final product.

[0047] In some preferred embodiments, in the step a, the extraction of ginger comprises the following steps:

[0048] a-1. Ginger is squeezed physically to obtain juice;

[0049] a-2. Add polyol A to the above juice, refrigerate, and filter to obtain the first filtrate;

[0050] a-3. The above filtrate is subjected to ultrafiltration, and the first ultrafiltrate is collected.

[0051] The extraction method of the dried ginger is as follows: the dried ginger is mixed with polyol A, ultrasonically extracted, the extract is subjected to ultrafiltration, and the second ultrafiltrate is collected...

Embodiment 1

[0076] Example 1 provides an anti-hair loss plant extract. The raw materials for preparing the plant extract include: 10 parts of dried ginger, 3 parts of red clover, 6 parts of arborvitae leaves, and 2 parts of mugwort leaves in parts by weight.

[0077] This example also provides the preparation method of above-mentioned anti-hair loss plant extract, comprises the following steps:

[0078] (1) Dried ginger is mixed with 1,3-propanediol in a weight ratio of 1:7, and 250W ultrasonic extraction is performed for 15 minutes to obtain an ultrasonic extract;

[0079] (2) Ultrafiltration is carried out to the ultrasonic extract of step (1), the molecular weight cut-off is 3000, and the ultrafiltrate is collected;

[0080] (3) Mix remaining raw materials except dried ginger, pulverize, cross 40 mesh sieves, obtain mixture;

[0081] (4) Add a mixed solvent of 1,3-propanediol and water with a volume ratio of 1:1, which is 6 times the weight of the mixture, to the mixture in step (3), ...

Embodiment 2

[0086] Embodiment 2 provides an anti-hair loss plant extract. In parts by weight, the preparation raw materials of the plant extract include: 30 parts of ginger, 6 parts of arborvitae leaves, 4 parts of Polygonum cuspidatum, 6 parts of Swertia japonica, 3 parts of Astragalus share.

[0087] This example also provides the preparation method of above-mentioned anti-hair loss plant extract, comprises the following steps:

[0088] (1) Ginger is physically squeezed to obtain juice;

[0089] (2) Add 1,3-propanediol to the juice in step (1), the mass ratio of juice to 1,3-propanediol is 1:4, stir evenly, refrigerate at 4°C for 5 hours, and filter to obtain the first filtrate;

[0090] (3) The first filtrate of step (2) is subjected to ultrafiltration, and the molecular weight cut-off is 3000, and the ultrafiltrate is collected;

[0091] (4) Mix remaining raw materials except ginger, pulverize, cross 40 mesh sieves, obtain mixture;

[0092] (5) Add a mixed solvent of 1,3-propanedi...

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Abstract

The invention discloses an anti-hair loss plant extract. Raw materials for preparing the plant extract are selected from at least two of rhizoma zingiberis recens, herba trifolii pratentis, herba swertiae bimaculatae, cacumen biotae, folium artemisiae argyi, rhizoma polygoni cuspidati and radix astragali. The plant composition has a synergistic effect, achieves an anti-hair loss effect through multiple channels and multiple target points, and action mechanisms mainly include enhancing the autophagy activity of the dermal papilla cells and promoting proliferation of the dermal papilla cells. Inaddition, the plant composition provided by the invention also has a remarkable oil control effect, and the anti-hair loss effect and the refreshing and comfortable use feeling are achieved by inhibiting scalp oil secretion.

Description

technical field [0001] The invention relates to the technical field of plant extracts, in particular to an anti-hair loss plant extract and its preparation method and application. Background technique [0002] Alopecia is a common clinical disease, which can be divided into types such as alopecia areata, seborrheic alopecia, chemotherapy-induced alopecia, and senile alopecia, among which alopecia areata and alopecia areata have the highest incidence rates. At present, the anti-hair loss products on the market have a single mechanism of action, and it is difficult to treat both symptoms and root causes. [0003] The best anti-hair loss drugs are western medicine minoxidil and finasteride, but long-term use will have obvious side effects. Among them, finasteride can cause allergic reactions such as itching, urticaria, and facial swelling. Women’s use can cause baby’s eczema. Birth defects and sexual dysfunction, minoxidil is likely to cause severe hirsutism on the face and li...

Claims

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Application Information

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IPC IPC(8): A61K8/9794A61K8/9761A61Q7/00A61Q19/00A61P17/14A61P17/10
CPCA61K8/9794A61K8/9761A61Q7/00A61Q19/008A61Q19/00A61P17/14A61P17/10A61K2800/805A61K2800/82
Inventor 刘青黄芳孔令姗周利丹卢伊娜田军
Owner SHANGHAI JAKA BIOTECH CO LTD
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